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|本期目录/Table of Contents|

白细胞介素-6与低氧性肺动脉高压关系的探究

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2012年第5期
页码:
663-666
栏目:
综述
出版日期:
2012-10-25

文章信息/Info

Title:
Relationship between interleukin-6 and hypoxic pulmonary hypertension
作者:
荆 琳1; 樊 荣2; 李 娟2; 裴建明2
(第四军医大学：1.口腔医学系学员14队，
2.生理学教研室 西安 710032)
Author(s):
JING Lin1;  FAN Rong2;  LI Juan2;  PEI Jian-ming2
(1.Cadet Battalion 14, Department of Stomatology, 2.Department of Physiology, Fourth Military Medical University, Xi’an 710032, Shaanxi, China)
关键词:
白细胞介素-6; 低氧; 肺动脉高压
Keywords:
interleukin-6;  hypoxia;  hypertension;  pulmonary
分类号:
R392.12
DOI:
-
文献标识码:
A
摘要:
肺动脉高压（PAH）是一种常见的临床症状，凡是能引起血管阻力增大、血流量增多的因素都可成为其诱因。低氧性肺动脉高压（HPH）则是以低氧性肺动脉收缩和低氧性肺血管重构引起的肺动脉压持续升高为特征的病症。急、慢性低氧均可引起白细胞介素-6（IL-6）的分泌，导致炎症细胞浸润，继而通过对动脉内膜的改建引起PAH。
Abstract:
Pulmonary artery hypertension (PAH) is a common syndrome that can be induced by stronger vascular resistance and increased blood flow. Hypoxic pulmonary hypertension (HPH) is a syndrome characterized by hypoxia-induced pulmonary artery resistance and hypoxia-induced pulmonary vascular remodeling. Both acute and chronic hypoxia can cause interleukin-6 secretion, which induces PAH through endarterial remodeling.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2012-02-11.
通讯作者：裴建明，教授，主要从事心血管生理学研究 Email:jmpei8@fmmu.edu.cn 共同
通讯作者：李娟，讲师，主要从事心血管生理学研究Email:lijuan2162008@163.com
作者简介：荆琳，本科生Email:jinglin314@126.com
更新日期/Last Update: 2012-11-16