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|本期目录/Table of Contents|

心脏血栓患者52例临床分析

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2013年第1期
页码:
54-056
栏目:
临床研究
出版日期:
2013-02-25

文章信息/Info

Title:
Clinical analysis of cardiac thrombus formation in 52 patients
作者:
张钰聪; 孔 强; 史力生; 高 静; 王彩荣; 李 康
(首都医科大学宣武医院心脏科，北京 100053)
Author(s):
ZHANG Yucong;  KONG Qiang;  SHI Lisheng;  GAO Jing;  WANG Cairong;  LI Kang
(Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China)
关键词:
心脏血栓; 房颤; 高敏C反应蛋白
Keywords:
cardiac thrombus formation;  atrial fibrillation;  high sensitive Creactive protein
分类号:
R541
DOI:
-
文献标识码:
A
摘要:
目的:分析52例经食管超声明确诊断心脏血栓患者临床病史、左心房及左心室内径、射血分数、心脏附壁血栓情况及检测的凝血指标、高敏C反应蛋白（hsCRP）等。方法： 病例回顾分析，选择2006年10月~2011年10月首都医科大学宣武医院住院患者新诊断证实心脏有血栓形成者52例。结果： 52例心脏血栓患者中，男性34例（65%），女性18例（35%），男性显著高于女性（P<005）。年龄18~83（60±16）岁。心功能（NYHA）分级Ⅲ级及以上31人，占60%。心房颤动是第1并发症，其次为缺血性脑血管病、高血压病、冠心病。血栓并发心房颤动患者中，心脏瓣膜病占47%。共发现70个栓子，左心耳发生率最高。按照血栓部位分组，发现左房及左心耳血栓患者左心房内径显著增大，其他部位血栓者左心室内径显著增大，差别均有显著性（P<005）。hsCRP在左房及左心耳血栓患者中低于其他部位血栓患者，两组之间差异显著（P<005）。结论： 房颤与血栓形成关联密切，左心耳部位血栓发生风险最高，临床上对心功能不全、房颤、缺血性脑血管病者要积极行经食道超声检查以明确诊断。
Abstract:
AIM:To determine the relationship between histories, left atrium and ventricle diameters, left ventricular ejection fraction (LVEF), thrombus formation, blood coagulation parameters and high sensitive Creactive protein (HsCRP). METHODS: According to the results of transesophageal echocardiography (TEE) examinations, data of 52 patients with cardiac thrombus formation were analyzed retrospectively. RESULTS: Of the 52 patients, 34 were male (654%) and 18 female (346%). Thirty one patients (654%) were in NYHA Class III or higher. Atrial fibrillation (AF) was the top complication followed by ischemic brain disease, hypertension and coronary heart disease. Altogether, 70 emboli were found and in 20 patients thrombus formations were in the atrial appendage. A significant difference was observed in gender, left atrium and ventricle diameters, and HsCRP (P<005). CONCLUSION: AF is one of the most important factors for cardiac thrombus formation. Left atrial appendage is a common site for thrombus formation. TEE is an optimal way to detect cardiac thrombus formation.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2012-09-04.作者简介：张钰聪，副主任医师，博士Email:zhangyucong@medmail.com.cn
更新日期/Last Update: 2013-03-20