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|本期目录/Table of Contents|

小G蛋白Rad的研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2013年第5期
页码:
589-591
栏目:
综述
出版日期:
2013-09-25

文章信息/Info

Title:
Research progress of small G protein Rad
作者:
胡保奎1; 牛丽丽1; 耿召华2
（1.北京军区总医院心内科，北京 100700；2.第三军医大学新桥医院心内科，重庆 400037）
Author(s):
HU Bao kui1;  NIU Li li1;  GENG Zhao hua2
(1.Department of Cardiology, General Hospital, Beijing Area Command, Beijing 100700, China; 2.Department of Cardiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China)
关键词:
小G蛋白; Rad蛋白; 心肌肥大; 肿瘤
Keywords:
small G protein;  rad protein;  cardiac hypertrophy;  tumor
分类号:
R329.28
DOI:
-
文献标识码:
A
摘要:
Rad蛋白是三磷酸鸟苷酸酶（GTPases）的Ras超家族成员之一，是新发现的小G蛋白。Rad蛋白在多种细胞中表达，参与心脏功能的维持，调控心肌细胞凋亡，抑制血管平滑肌迁移，Rad蛋白表达的异常与人类的肿瘤发生发展密切相关。Rad蛋白在生物学和医学中都有重要作用，本文就Rad蛋白的研究进展做一综述。
Abstract:
Rad protein is one of the members of the Ras superfamily of guanosine triphosphatases (GTPases) and is a newly discovered small G protein. Rad is expressed in a variety of cells involved in maintaining heart functions, regulating myocardial apoptosis and inhibiting migration of vascular smooth muscle. Abnormal Rad expression is closely related to human tumor development. Rad plays an important role in biology and medicine. This paper reviews recent progress in Rad protein research.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期: 2013-02-20.基金项目：国家自然科学基金项目资助（81070093） 通讯作者：牛丽丽，教授，主要从事动脉粥样硬化相关研究 Email：niulili2003@126.com 作者简介：胡保奎，硕士生 Email：641117506@qq.com
更新日期/Last Update: 2013-09-30