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|本期目录/Table of Contents|

不同病因所致心力衰竭的预后分析

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2013年第6期
页码:
668-672
栏目:
临床研究
出版日期:
2013-11-25

文章信息/Info

Title:
Prognostic value of etiology in patients with heart failure
作者:
张恒亮1; 张 培1; 姚亚丽2
(兰州大学：1.第一临床医学院，甘肃 兰州 730000，2.第一医院心内科，甘肃 兰州 730000)
Author(s):
ZHANG Heng liang1;  ZHANG Pei1;  YAO Ya li2
(1.First Clinical Medical School, Lanzhou University, 2.Department of Cardiology, First Hospital of Lanzhou University, Lanzhou 730000, Gansu, China)
关键词:
心力衰竭; 病因; 预后
Keywords:
heart failure;  etiology;  prognosis
分类号:
R541.9
DOI:
-
文献标识码:
A
摘要:
目的:探讨不同病因所致心力衰竭（心衰）对患者预后的影响。方法:回顾性分析2007年1月~2010年12月兰州大学第一医院心内科收治住院的556例心衰患者的临床资料，并进行电话随访，确认患者是否死亡。根据引起心衰的病因不同将研究对象分为冠心病组、高血压病组、扩张型心肌病组（扩心病组）、心脏瓣膜病组和多病因组。Cox比例风险模型评价不同病因组患者的预后差异，并建立KaplanMeier生存曲线。结果:共纳入分析患者513人，截止随访结束，死亡231人，占45%；不同病因组患者的年龄、心功能分级、左室射血分数等指标有明显差异（P<0.05）；多因素Cox比例风险模型分析显示冠心病组和扩心病组的死亡风险分别为心脏瓣膜病组的2.517倍（P<0.05）和2.480倍（P<0.05）。结论:心衰患者不同病因的预后不同。
Abstract:
AIM:To study the prognostic value of etiology in patients with heart failure (HF). METHODS: Data of inhospital patients with HF in our hospital between January 2007 and December 2010 were investigated and the patients were followedup by telephone. Patients were classified into the following etiology groups, namely, coronary heart disease, hypertension, dilated cardiomyopathy, valvular disease. Multifactors and clinical characteristics in each group were analyzed. Cox proportional hazards analyses were conducted to examine the difference in mortality. RESULTAS: A total of 513 patients with heart failure were enrolled; 231 died by the end of the followup period with a mortality rate of 45%. Significant differences were found in ages, NYHA classes and LVEF among the different groups (P<0.05). Multivariate analysis showed that HR in patients with coronary heart disease and dilated cardiomyopathy were, respectively, 2.517 times and 2.480 times than in patients with valvular disease (P<0.05). CONCLUSION: Patients with HF have a poor prognosis and high mortality rate. Different etiologies of heart failure demonstrate different clinical characteristics and prognoses.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2013-05-26.通信作者：姚亚丽，主任医师，主要从事心力衰竭的研究 Email：yaoyalifs@yahoo.com.cn 作者简介：张恒亮，硕士生 Email：zhl8813@yahoo.cn
更新日期/Last Update: 2013-11-20