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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

2014年第6期

页码:

655-658

栏目:

临床研究

出版日期:

2014-06-25

文章信息/Info

Title:

Correlation analysis of coronary artery flow after intervention and target vessel diameter

作者:

韩雅君; 张 园; 田志强; 赵 平; 赵炜祎

(内蒙古自治区人民医院心内科，内蒙古 呼和浩特 010017)

Author(s):

HAN Ya-jun;  ZHANG Yuan;  TIAN Zhi-qiang;  ZHAO Ping;  ZHAO Wei-yi

(Department of Cardiology, People’s Hospital of Inner Mongolia Autonomous Region, Huhhot 010017, Inner Mongolia, China)

关键词:

参考血管直径; 血流; 冠状动脉介入治疗

Keywords:

reference vessel diameter;  slow flow;  percutaneous coronary intervention

分类号:

R541.4

DOI:

-

文献标识码:

A

摘要:

目的:评价冠状动脉支架术后血流与血管直径的相关性。方法： 对192例行冠状动脉介入(PCI)治疗患者的224支靶血管进行定量冠状动脉造影（QCA）分析和术前术后TIMI帧数分析。术前术后TIMI帧数差值进行三分位数分组，≤2为“慢血流组”，3~9为“正常血流组”，≥10为“快血流组”。同时根据参考血管直径分成大血管组（≥4 mm）、正常血管组（2.76~4.0 mm）、小血管组（≤2.75 mm）。对3组的冠状动脉病变特征和基线资料进行比较。比较不同直径血管的病变特征。对术后血流的相关危险因素进行多元线性回归分析。结果： 慢血流组、正常血流组和快血流组患者靶血管参考血管直径分别为(3.4±0.7) mm、(3.2±0.7) mm和(3.2±0.7) mm，P<0.05。大血管在慢血流组、正常血流组和快血流组的比率分别为29%（23/78）、10%（8/80）和14%（9/66），P<0.01。≥4 mm血管组和<4 mm血管组的斑块面积分别为(23±11) mm2和(15±8) mm2，P<0.01。多元回归分析PCI术后血流状态的危险因素为年龄（P<0.05）和参考血管直径（P<0.01）。结论： PCI术后血流与冠状动脉血管直径相关。血管直径越大发生介入术后慢血流的几率越高。

Abstract:

AIM:To evaluate the correlation between coronary artery diameter and slow flow after percutaneous coronary intervention (PCI). METHODS: Quantitative coronary angiography (QCA) and thrombolysis in myocardial infarction frame count (TIMI frame count) were analyzed in 224 target vessels in 192 patients with PCI. The difference of TIMI frame count before and after PCI 2 was defined as “slow flow group,” 3-9 as “normal flow group” and ≥10 as “fast flow group” according to tertile. The 224 target vessels were divided into diameter ≥4 mm group and <4 mm group. Coronary artery lesion characteristics and baseline information were compared among the three groups. Coronary artery lesion characteristics were also compared in vessels of different diameters. Multiple linear regression analysis was performed in coronary artery flow after PCI and its related risk factors. RESULTS: The reference vessel diameters of target vessels were (3.4±0.7) mm, (3.2±0.7) mm and (3.2±0.7) mm (P<0.05). The ratio of big vessels in the three groups were 29% (23/78), 10% (8/80) and 14% (9/66), P<0.01. The plaque areas were (23±11) mm2 and (15±8) mm2 in diameter ≥4 mm group and <4 mm group (P<0.01). The risk factors for coronary artery flow after PCI were age (P<0.05) and reference vessel diameter (P<0.01) in multiple linear regression analysis. CONCLUSION: Slow flow after PCI is related to coronary artery diameter: the bigger the vascular diameter, the higher the risk of slow flow after PCI.

参考文献/References

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备注/Memo

备注/Memo:

收稿日期：2014-01-19.
基金项目：内蒙古自治区人民医院基金项目资助（20110910）
作者简介：韩雅君，博士Email：junyahan@sina.com

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更新日期/Last Update: 2014-07-10