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|本期目录/Table of Contents|

体外循环与非体外循环下行CABG对肾功能不全患者肾功能影响的比较

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第1期
页码:
71-072,082
栏目:
临床研究
出版日期:
2014-09-25

文章信息/Info

Title:
Comparison of on-pump and off-pump coronary artery bypass in patients with renal insufficiency
作者:
薛 军; 陈晓英
(武汉亚洲心脏病医院心内科，湖北 武汉 430022)
Author(s):
XUE Jun;  CHEN Xiao-ying
(Department of Cardiology, Wuhan Asian Heart Hospital, Wuhan 430022, Hubei, China)
关键词:
肾功能不全; 体外循环; 非体外循环; 冠状动脉旁路移植术
Keywords:
renal inadequacy;  on-pump;  off-pump;  coronary artery bypass
分类号:
R543.3
DOI:
-
文献标识码:
A
摘要:
目的:比较在体外循环与非体外循环下行冠状动脉旁路移植术（CABG）对患者肾功能的影响。方法： 我院40位择期行CABG的慢性肾功能不全患者，随机分为两组，每组20例，分别在在体外循环与非体外循环下行CABG。术前及术后1、3、7 d测定血肌酐值并计算肌酐清除率。结果： 体外循环组患者术后血肌酐值显著高于非体外循环组，其肌酐清除率较术前显著下降。结论：肾功能不全患者在体外循环与非体外循环下行CABG，前者更易加重肾功能损害。
Abstract:
AIM:To compare the effect of on-pump and off-pump coronary artery bypass surgery in patients with chronic renal insufficiency. METHODS: Forty patients with chronic renal insufficiency who underwent elective surgery were divided randomly into two groups: on-pump cardiopulmonary bypass group (OCPB) (n=20) and off-pump CPB group (n=20). Serum creatinine (Scr) was detected and creatine clearance (Ccr) was calculated before and 1, 3 and 7 days after operation. RESULTS: After surgery, Scr in OCPB group was obviously higher than in off-pump CPB group and Ccr was strikingly lower compared with preoperative values. CONCLUSION: Compared with off-pump coronary artery bypass, on-pump coronary artery bypass is more likely to aggravate renal dysfunction in patients with chronic renal insufficiency.

参考文献/References

[1]Omeroglu SN,Kirali K,Güler M,et al.Midterm angiographic assessment of coronary artery bypass grafting without cardiopulmonary bypass[J].Ann Thorac Surg,2000,70(3):844-849,850.
[2]Hayashida N,Teshima H,Chihara S,et al.Does off-pump coronary artery bypass grafting really preserve renal function?[J].Circ J,2002,66(10):921-925.
[3]万彩红,董培青.体外循环与急性肾功能衰竭[J].心肺血管病杂志,2003,22(3):190-192.
[4]汪曾炜,刘维永,张宝仁.心脏外科学[M].北京:人民军医出版社,2003:258.

备注/Memo

备注/Memo:
收稿日期：2014-04-08.
作者简介：薛军,主治医师Email:xuejun_1999@163.com
更新日期/Last Update: 2015-01-20