我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

平均血小板体积与冠心病的关系

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第2期
页码:
248-250
栏目:
综述
出版日期:
2015-11-25

文章信息/Info

Title:
Relationship between mean platelet volume and coronary heart disease
作者:
李 萌; 王 萍; 陈 晖
（首都医科大学北京友谊医院心血管中心，北京 100050）
Author(s):
LI Meng;  WANG Ping;  CHEN Hui
(Cardiovascular Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)
关键词:
平均血小板体积; 冠状动脉疾病; 高血压; 糖尿病; 吸烟; 高脂血症
Keywords:
mean platelet volume;  coronary heart disease;  hypertension;  diabetes;  smoking;  hyperlipidemia
分类号:
R543.3
DOI:
-
文献标识码:
A
摘要:
血小板形态和功能的变化是心脑血管疾病发病机制中的重要独立危险因子之一。血小板在冠心病(CHD)的发生、发展过程中具有重要作用，但目前尚无明确反映血小板功能的指标，近年多项研究发现血小板参数中的平均血小板体积（MPV）是反映血小板活化的一个重要指标。检测MPV是评估血小板功能一种简单、快捷的方法，对预测CHD临床事件的发生具有一定的临床意义。
Abstract:
The change of form and function of platelets is one independent risk factor for cardiovascular diseases. Platelets play an important role during the occurrence and development of coronary heart disease, but there is no definite index that can reflect platelet function. In recent years, many studies have found that mean platelet volume (MPV) is an important index that reflects platelet activation. Detecting MPV is a simple and fast way to assess platelet function and has clinical significance in predicting clinical events of coronary heart disease.

参考文献/References

[1]Boos CJ,Beevers GD,Lip GY.Assessm ent of platelet activation indices using theADVIAT M 120 am ongst‘high-risk’ patients with hypertension[J].Ann Med,2007,39(1):72-78.
[2]旷 旭.原发性高血压患者血小板参数的变化及意义[J].中国医药指南,2012,10(15):405-406.
[3]张天寿，李 平.糖尿病患者血小板参数变化的探讨[J].甘肃中医,2006,19(3):21-22.
[4]Carlsson M,Wessman Y,Almgren P,et al.Hgh levels of nonesterified fattyacids are associated with increased familial risk of cardiovascular disease[J].Arterioscler Throm Vasc Biol,200020(6):1588-1594.
[5]Sharpe PC,Trinick T.Mean platelet volume in diabetes mellitus[J].Q J Med,1993,86(11):739-742.
[6]邢 渊，宋成功.超重肥胖与血小板参数的相关性分析[J].甘肃中医,2010,29(3):258-260.
[7]Yarlioglues M,Ardic I,Dogdu O,et al.The acute effects of passive smoking on mean platelet volume in healthy volunteers[J].Clin Hemorheol Microcirc,2010,45(2-4):359-364.
[8]李建新,王 禹.吸烟对大鼠血小板功能的影响[J].中国病原生物学杂志, 2010,5(6):475-476.
[9]Huang RY,Chen GG.Cigarette smoking, cyclooxygenase-2pathway and cancer[J].Biochim Biophys Acta,2011,1815(2):158-169.
[10]庄爱周，吴国友，马小红，等.吕远栋.血脂异常人群血小板参数和聚集功能变化及临床意义[J].心脑血管病防治,2009,9(5):373-375.
[11]许文亮，武 越，惠 波，等.冠心病患者血小板平均体积的变化及相关因素研究[J].冠心病研究,2012,27(4):262-265.
[12]杨 平，方 堃，张丽萍，等.血脂及年龄对血小板参数的影响和相关性分析[J].职业与健康,2011,27(9):992-994.
[13]Li D,Turner A,Sinclair AJ.Relationship between platelet phospholipid FA and mean platelet volume in heathy men[J].Lipid,2002,37(9):901-906.
[14]彭黎明，梁 超.血脂对血小板体积影响研究[J].血栓与止血,2006,12(6):272-275.
[15]杜雪霞.冠心病患者血小板活化指标和血小板参数的检测及临床意义[J].广东医学院学报,2006,24(5):486-487.
[16]Yilmaz MB,Cihan G,Guray Y,et al.Role of mean platelet volume in triagging acute coronary syndromes[J].J Thromb Thrombolysis,2008,26(1):49-54.
[17]许文亮，徐 莉，王 旭，等.急性冠脉综合征血小板平均体积的相关性研究[J].岭南心血管病杂志,2012,18(1):20-24.
[18]许文亮，惠 波，武 越，等.急性ST段抬高型心肌梗死患者平均血小板体积的变化及与冠状动脉影像的关系[J].冠心病研究,2012,27(4):262-265.
[19]Varol E,Icli A,Ozaydin M,et al.Mean platelet volume is elevated in patients with myocardial infarction with normal coronary arteries,as in patients with myo-cardial infarction with obstructive coronary artery disease[J].Scand J Clin Lab Invest,2009,69(5):570-574.
[20]Martin JF,Bath PM,Burr ML.Influence of platelet size on outcome after myocardial infarction[J].Lancet,1991,338(8780):1409-1411.
[21]Duygu H,Turkoglu C,Kirilmaz B,et al.Effect of mean platelet volume on postintervention coronary blood flow in patients with chronic stable angina pectoris[J].J Invasive Cardiol,2008,20(3):120-124.
[22]Sen N,Basar N,Maden O,et al.Increased mean platelet volume in patients with slow coronary flow[J].Platelets,2009,20(1):23-28.
[23]Yang A, Pizzulli L, Luderitz B. Mean platelet volume as marker of restenosis after percutaneous transluminal coronary angioplasty in patients with stable and unstable angina pectoris［J］. Thromb Res, 2006, 117(4):371-377.
[24]Goncalves SC, Labinaz M, Le May M, et al. Usefulness of mean platelet volume as a biomarker for long-term outcomes after percutaneous coronary intervention［J］. Am J Cardiol, 2011, 107(2):204-209.
[25]Maden O, Kacmaz F, Selcuk H, et al. Relationship of admission hemato-logical indexes with myocardial reperfusion abnormalities in acute ST segment elevation myocardial infarction patients treated with primary per-cutaneous coronary inierventions［J］. Can J Cardiol, 2009, 25(6):164-168.
[26]Pastuszczak M, Kotlarz A, Mostowik M, et al. Prior simvastatin treatment is associated with reduced thrombin generation and platelet activation in patients with TG acute ST-segment elevation myocardial infarction［J］. Thromb Res, 2010, 125(5):382-386.

备注/Memo

备注/Memo:
收稿日期：2014-10-19.
通讯作者：陈晖，主任医师，主要从事冠心病和心力衰竭研究 Email：Chenhui72@medmail.com.cn
作者简介：李萌，硕士生 Email：vickylm1989@163.com
更新日期/Last Update: 2016-04-25