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|本期目录/Table of Contents|

大蒜素对老年高脂血症患者血脂及体质量指数的影响

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第5期
页码:
565-567
栏目:
临床研究
出版日期:
2016-04-25

文章信息/Info

Title:
Effects of garlic on body mass index and serum lipids in elderly patients with hyperlipidemia
作者:
王 瑞1; 樊 颍2; 肖林平1; 陈鹰军1; 张卫国1; 贺东风1; 李 泱3
（1.解放军451医院门诊部，陕西 西安 710054；
2.空军装备研究院门诊部，北京 100085；
3.解放军总医院老年心血管病研究所，北京 100853）
Author(s):
WANG Rui1;  FAN Ying2;  XIAO Lin-ping1;  CHEN Ying-jun1;  ZHANG Wei-guo1;  HE Dong-feng1;  LI Yang3
(1.Outpatient Department, PLA 451 Hospital, Xi’an 710054, Shaanxi, China；
2.Outpatient Department, Equipment Academy of Air Force, Beijing 100085, China；
3. Institute of Geriatric Cardiology, PLA General Hospital, Beijing 100853, China)
关键词:
大蒜素; 高脂血症; 血脂; 体质量指数; 老年
Keywords:
garlic;  hyperlipidimia;  serum lipids;  body mass index;  elderly patients
分类号:
R972.6
DOI:
-
文献标识码:
A
摘要:
目的 探讨大蒜素对老年高脂血症患者体质量指数（BMI）及血脂水平的影响。方法 选择门诊就诊血脂异常的老年患者，将符合标准160例患者分为试药组（n=80）和安慰剂组（n=80），试药组予大蒜素胶囊，安慰剂组服用安慰剂胶囊；观察两组治疗前后一般状况、BMI、血清总胆固醇（TC）、三酰甘油（TG）、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇（HDL-C）、肝、肾功能等的变化。结果 127例患者完成治疗，其中试药组65例，安慰剂组62例；试药组TC（4.8±1.3）mmol/L、TG（1.4±1.1）mmol/L、LDL-C（2.6±0.7）mmol/L、BMI(25.1±5.2)均显著低于安慰剂组（均P<0.05），HDL-C（1.5±0.7）mmol/L显著高于安慰剂组（P<0.05）。结论 大蒜素能有效降低老年高脂血症患者血脂水平。
Abstract:
AIM To observe the effects of garlic on body mass index and serum lipids in elderly hyperlipidemia patients. METHODSOne hundred and sixty elderly hyperlipidemia patients were divided into treatment group (n=80) and control group (n=80). The treatment group was treated with garlic capsules, whereas the control group was treated with placebo capsules. The general status, body mass index (BMI), serum total cholesterol (TC), serum triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), blood viscosity, and liver and kidney functions were compared before and after treatment. RESULTSOne hundred and twenty-seven patients completed the treatment. In the treatment group (n=65), BMI, TC, TG and LDL-C were, respectively, (25.1±5.2), (4.8±1.3) mmol/L, (1.4±1.1) mmol/L and (2.6±0.7) mmol/L, lower than those in the control group (n=62), and HDL-C was (1.5±0.7) mmol/L, higher than that in the control group (P<0.05). CONCLUSIONGarlic compared with placebo can effectively reduce serum lipids and body mass index in elderly hyperlipidemic patients.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2015-10-09.
通讯作者：李泱，教授，主要从事心血管疾病研究 Email：liyangbsh@163.com
作者简介：王瑞，主任医师，硕士 Email：ruitao_1991@aliyun.com
更新日期/Last Update: 2016-04-13