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Title:: Protective effect and molecular mechanism of omega-3 fatty acids on cardiovascular system

作者:: 邱雅¹; 曹丰²; （解放军总医院：1.老年医学研究所，2.心内科，北京100853）

Author(s):: QIU Ya¹; CAO Feng²; (1.Institute of Geriatrics, 2.Department of Cardiology, PLA General Hospital, Beijing 100853, China)

关键词:: ω-3多不饱和脂肪酸; 心血管系统; 二十碳五烯酸; 二十二碳六烯酸; 分子机制

Keywords:: omega-3 PUFAs; cardiovascular system; eicosapentenoic acid; docosahexenoic acid; molecular mechanisms

分类号:: R322.1

DOI:: -

文献标识码:: A

摘要:: ω-3多不饱和脂肪酸（ω-3 PUFAs）是人体所需的必须脂肪酸，大量证据表明其对心血管具有保护作用，然而机制尚不明确。二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）是鱼油来源的ω-3 PUFAs，可有效防治心血管疾病，相关研究报道较多。本文主要对ω-3 PUFAs的基本特征和对心血管系统的保护作用及其机制研究做一综述。

Abstract:: Omega-3 fatty acids (omega-3 PUFAs) are essential fatty acids in human tissues. Substantial research suggests that Omega-3 exerts a protective effect on cardiovascular system. However, the molecular mechanism is still unclear. Eicosapentenoic acid (EPA) and docosahexenoic acid (DHA) are two kinds of omega-3 PUFAs from fish oils, which have been cited for prevention and treatment of cardiovascular diseases. This paper reviews the basic characteristics of omega-3 PUFAs and their molecular mechanisms of mediating or modulating protective effects on the cardiovascular system.

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ω-3多不饱和脂肪酸对心血管的保护作用及其分子机制研究

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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