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急性心肌梗死患者心率变异性与血浆儿茶酚胺类物质和甲状腺激素的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1998年第4期
页码:
227-229
栏目:
论著
出版日期:
1998-07-01

文章信息/Info

Title:
The relation between heart rate variability and plasma catecholamines and thyroid hormone in acute myocardial infarction
作者:
王明空1　李春生1　韩永生2　徐红岩1　胡淑贞1
解放军152医院　1心内科 2检验科 平顶山 467000
Author(s):
Wang Mingkong1 ;  Li Chunsheng1 ;  Han Yongsheng1;  Xu Hongyan1;  Hu Shuzhen1
Hospital 152, PLA , Pingdingshan, Henan 467000
关键词:
心肌梗死　自主神经　心率变异性　儿茶酚胺　甲状腺激素
Keywords:
myocardial infarct 　heart rate variability 　autonomic nervous system 　catecholamine　thyroid hormone
分类号:
-
DOI:
-
文献标识码:
-
摘要:
为探讨心率变异时域分析评价急性心肌梗死(AMI)患者心脏自主神经活动的变化, 作者对26例AMI患者、27例陈旧性心肌梗死患者及20例正常人的血浆去甲肾上腺素、肾上腺素及甲状腺激素(T3, T4) 进行测定, 同时与心率变异性进行对比。证明AMI早期存在心脏迷走神经活性降低, 交感神经活性相对占优势; 交感肾上腺素能系统及甲状腺分泌全面激活。作者认为, 心率变异时域分析是一种检测心脏自主神经功能较敏感、可靠的无创性方法, 可为预测心脏事件的发生提供重要依据。
Abstract:
The time2-domain measurements of heart rate variability (HRV) were used, and plasma catecholamines and thyroid hormone were comparatively studied in 26 patients with acute myocardial infarct(AMI), 27 with remote myocardial infarct (OMI) and 20 control subjects. It was demonstrated that the parasympathetic depression, sympathetic predominance, overactivity of the adrenergic system and thyroid hormone secretion were present in patients with AMI. The time-domain measurements of HRV might be a feasible method for evaluating cardiac autonomic activity. It can facilitate the prediction of cardiopathy in high risk patients so that prevention or finely treatment can be ensured.

参考文献/References

［1］Wabb SW , Adgey AAJ , Pantvidge JF. Autonomic disturbance at onset of acute myocardial infarction. Br Med J , 1971; 3: 89.

［2］Mitsui A. High-performance liquid chromatography of plasma catecholamines using 1.2-diphenyl-ethylenediamine as precolum flourescence derivatization reagent. J Chromatogy , 1985; 344: 61.

［3］胡红桃, 宋有城, 朱　俊, 等.心率变异性.临床心电学杂志, 1995; 4 (1) : 23.

［4］寥禹林, 贾世纯, 付　真, 等.慢性充血性心力衰竭患者的心率变异性分析.临床心血管病杂志, 1995; 11 (6) : 344.

［5］Levy MN , Yang T, Wallick DW , et al. Assessment of beat-bybeat control of heart rate by the autonomic nervous system:Moleuclar Biology techniques are necessary, but not sufficient.J Cardiovasc Electrophysiol, 1993; 4 (2) : 183.

［6］Ganguly PK, Dhalla KS, Shao Q , et al. Differential changes in sympathetic activity in left and right ventricles in congestive heart failure after myocardial infarction. Am Heart J , 1997; 133(3) : 340.

[7]张镜如.生理学.第4 版.北京: 人民卫生出版社, 1996; 387～403.

[8]Kleiger RE, Miller JP, Bigger JT, et al. Decreased heart rate variability and its association with increased mortality after AMI. Am J Cardiol, 1987; 59 (2) : 256.

[9]王家宁, 胡大一.心率变异的频域分析与心血管药物.心血管病学进展, 1995; 16 (3) : 155.

备注/Memo

备注/Memo:
(收稿1997-12-05　修回1998-05-12)
更新日期/Last Update: 1998-07-01