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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

1999年第2期

页码:

91-94

栏目:

论著

出版日期:

1999-03-01

文章信息/Info

Title:

Changes of right ventricular structures and functions in hypertensive patients and analysis of related factors

作者:

王兆禹¹　李佐才²　张开宁³　程小床¹　刘艳红²

昆明医学院　1第一附属医院干部医疗科　2第一附属医院心内科　3卫生系统计学教研室　650032

Author(s):

Wang Zhaoyu1; Li Zuocai2;  Zhang Kaining3;  Cheng Xiaomi1; Liu Yanhong2

First Affiliated Hospital of Kunming Medical College, Kunming 650032

关键词:

高血压病　右心室结构和功能

Keywords:

hypertension　right ventricular structure and function

分类号:

-

DOI:

-

文献标识码:

-

摘要:

本文研究高血压病患者右心室结构和功能变化、影响因素及其与左室结构和功能变化的关系。分析89例未经治疗的Ⅰ或Ⅱ期高血压病患者与82例正常对照者之间按超声心动图测算的右室解剖结构和功能指标的差异、相关关系及其与左室对应指标及其他影响因素的相关性。结果显示: 高血压病患者右室前壁厚度增加, 舒张期充盈受损, 经协方差分析将年龄、性别、体重指数及心率等的影响剔除之后, 差异仍存在显著性。收缩功能指标无显著性变化。右室结构和功能变化与血压水平和高血压所致的左室结构和功能变化之间有显著性相关关系。年龄、性别、体重指数及心率也是影响右室结构和功能测值的可能因素。

Abstract:

The study was carried out to investigate the changes of right ventricular structures,functions, and their associations with related factors and with the changes of indices of left ventricular structures and functions in hypertensive patients.Indices of the right ventricular structures and function smeasured and calculated by echocardiographic method in eighty nine untreated patients with essential hypertension of Ⅰor Ⅱstage and eighty two normotensive control subjects were studied.The differences of the indices between hypertensive and normotensive groups were compared and correlations of the indices of right ventricular structures and functions with related factors and with the indices of left ventricular structures and functions were analysed.Results showed that the thickness of right ventricular anterior wall increased and right ventricular diastolic filling function decreased.The differences of the indices of right ventricular structures and functions between the hypertensive and normotensive groups were statistically significant which persisted even after adjusted for age, sex, body mass index (BMI) and heart rate (HR) by covariance analysis.No significant changes of the indices of right ventricular contractile function were found in hypertensive patients.It was found that statistically significant correlations existed between the changes of indices of right and left ventricular structures and functions.Besides the level of blood pressure and extent of hypertensive changes of left ventricular structures and functions, age, sex, BMI and HR were factors affecting the indices of right ventricular structures and functions too.

参考文献/References

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［2］Nogueira JB.Arterial hypertension and the right heart.hemodynamic and echocardiographic study. Rev Port Cardiol, 1991; 10:837.

［3］黄生宁.分子心脏病学.见: 陈国伟, 郑宗锷主编. 现代心脏内科学.第1版.长沙: 湖南科学技术出版社, 1994: 1305.

［4］ Abergel E, Chatellier G, Toussaint P, et al.Doppler-derived pulmonary arterial systolic pressure in patients with known systemic arterial pressures.Am J Cardiol, 1996; 77: 767.

[5]Ghali JK, Liao YL , Cooper RS, et al.Changes in pulmonary hemodynamics with aging in a predominantly hypertensive population.Am J Cardiol, 1992; 70: 367.

[6]陈大年, 徐文渊, 方美菊, 等.超声心动图对高血压病患者右室功能的研究.临床心血管病杂志, 1995; 11 (3) : 175.

[7]Habib GB, Zoghbi WA.Doppler assessment of right ventricular filling dynamics in systemic hypertension: comparison with left ventricular filling.Am Heart J , 1992; 124: 1313.

[8]Cittadini A , Fazio S, Stromer H, et al.Optimal determination of right ventricular filling dynamics in systemic hypertension.Am Heart J , 1995; 130: 1074.

[9]Chakko S, de Marchena E, Kessler KM , et al.Right ventricular diastolic function in systemic hypertension.Am J Cardiol, 1990;65: 1117.

[10]Gabriel B,William A , Zoghbi M.Doppler assessment of right ventricular filling dynamics in hypertension.Comparison with left ventricular filling.Am Heart J , 1992; 124: 1313.

[11]王兆禹, 张开宁, 程小床, 等.健康成人右心收缩间期及其影响因素.心功能杂志, 1997; 9 (1) : 15.

[12]Gidding SS, Xie XY,Liu K, et al.Cardiac function in smokers and nonsmokers: The CARDIA Study.J Am Cool Cardiol, 1995; 26:211.

备注/Memo

备注/Memo:

(收稿1998-05-11　修回1998-10-13)

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更新日期/Last Update: 1999-03-01