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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

1999年第4期

页码:

228-229

栏目:

论著

出版日期:

1999-07-01

文章信息/Info

Title:

Hemorheological changes in acute ischemic region of dog due to coronary stenosis caused by laser irradiation on blood

作者:

杨继庆¹　张建保¹　王跃民²　范 云¹

第四军医大学　1物理学教研室　2生理学教研室,西安 710032

Author(s):

Yang Jiqing1;  Zhang Jianbao1; Wang Yuemin2;  Fan Yun1

1Department of Physics, 2Department of Physiology, Fourth Military Medical University,Xi’an 710032

关键词:

冠状动脉疾病　激光疗法　血液流变学

Keywords:

myocardial ischemia　coronary disease　laser therapy　hemorheology

分类号:

-

DOI:

-

文献标识码:

-

摘要:

健康杂种犬,开胸分离冠状动脉前降支,并造成冠状动脉狭窄。在狭窄120 min后将HeNe 激光(输出功率2. 46±0.11 mW) 经石英光纤插入下肢体大动脉,照射60 min。照射后其全血高切和低切粘度较照射前各减少11%和14% , 血浆粘度降低6%,红血细胞压积减少5%,纤维蛋白原下降14%, 均变化显著。对照组则无显著性变化。结果表明激光血管内照射(ILIB) 可降低纤维蛋白原浓度, 改善红细胞的变形性, 进而导致血浆粘度与全血粘度降低, 改善血液的流动性。

Abstract:

HeNe laser irradiation on blood(ILIB)was applied to the model with severe stenosis of the left anterior descending coronary artery from healthy dogs. After 120 min of the stenosis HeNe laser was input into the lower limb artery with an optical fiber and the radiation lasted 60 min. The experiment showed that after the radiation, the whole blood high shear viscosity, the whole blood low shear viscosity, plasma viscosity, and hemotacrit level and fibrinogen level decreased 11%,14%,6%,5% and 14% respectively (P<0.05),as compared with those before the radiation. But no changes were observed in the control group. The results indicate that ILIB can improve the hemorheological performance and fluidity of blood in the ischemic region.

参考文献/References

［1］刘红珍, 包兴昌. 低强度He-Ne激光血管内照射血液治疗脑梗塞患者作用机理的研究. 激光杂志, 1998; 19 (1) : 58.

［2］董为人. 低能量激光血管内照射复合治疗糖尿病性血管病变.应用激光, 1992; 12 (5) : 234.

［3］冯晓滨, 臧益民, 吴作舟, 等. 犬冠脉前降支缺血区早期局部血液粘度变化. 第四军医大学学报, 1989; 10 (6) : 402.

［4］Master E. The biostimulative effect of laser beam. Laser Basic Biomed Res. 1982; 22 (1) : 4.

［5］何作云, 尹翠云, 丁秋华. 人体血液流变学特性正常范围及其机理的初探. 中国血液流变学杂志, 1992; 2 (1) : 16.

备注/Memo

备注/Memo:

(收稿1999-04-13)

常用功能

更新日期/Last Update: 1999-07-01