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血府逐瘀汤对犬心肌缺血时左心室收缩时间间期的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
1999年第4期
页码:
230-231
栏目:
论著
出版日期:
1999-07-01

文章信息/Info

Title:
Effects of xuefu zhuyu decoction on left ventricular systolic time intervals in myocardial ischemia in dogs
作者:
李树壮 姜艳华 丁鸿雁 王允杰 曲秋莲 朱 波 马丽旭
解放军大连医学高等专科学校生理学教研室,大连 116017
Author(s):
Li Shuzhuang Jiang YanhuaDing HongyanWang YunjieQu Qioulian Zhu BoMa Lixu
PLA Dalian Junior College of Medicine,Dalian 116017
关键词:
血府逐瘀汤 心肌缺血 收缩时间间期
Keywords:
xuefu zhuyu decoction  myocardial ischemia  systolic time interval
分类号:
-
DOI:
-
文献标识码:
-
摘要:
在12条麻醉开胸犬上,用微米狭窄器缩窄冠脉造成急性心肌缺血,以左心室排血时间(LVET)、排血前时间(PEP)、等容收缩时间(ICT)、PEP/LVET比值和ICT/LVET比值为指标,观察心肌缺血时血府逐瘀汤用药前后心脏功能的改变。结果表明,急性心肌缺血时LVET缩短,PEP,ICT,PEP/LVET值增大,给药后,心脏功能明显好转。
Abstract:
Acute myocardial ischemia was caused by a micrometer constrictor in 12 open-chest mongrel dogs under anesthesia. The effect of xuefu zhuyu decoction on myocardial ischemia models was observed by measuring the left ventricular ejection time (LVET),pre-ejection period (PEP), isovolumic contraction time (ICT),PEP/LVET ratio and ICT/LVET ratio. The results showed that the PEP,ICT,PEP/LVET and ICT/LVET were significantly increased, the LVET was shortened in myocardial ischemia. In the treated group after taking the drug, the heart function was significantly improved.

参考文献/References

[1]陈士良, 臧益民, 潘 真, 等. 冠脉狭窄对心脏功能的影响. 中国病理生理杂志, 1988; 4 (5) : 276.

[2]Tei C,Ling LH, Hodge DO, et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducibl emeasure of cardiac function-a study in normals and dilated cardiomyopathy. J Cardiol, 1995; 26 (6) : 357.

[3]Scalvini S,Volterrani M ,Vitacca M , et al. Respiratory and haemodynamic modifications during right heart catheterization in COLD patients. Monaldi Arch Chest Dis, 1995; 50 (6) : 438.

[4]李树壮, 臧益民, 杨继庆, 等. 潘生丁对不同程度缺血心脏的作用. 第四军医大学学报, 1990; 11 (3) : 215.

备注/Memo

备注/Memo:
(收稿1999-06-29)
更新日期/Last Update: 1999-07-01