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阻塞性睡眠呼吸暂停综合征心率变异性的变化及其意义(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第5期
页码:
372-373, 376
栏目:
论著
出版日期:
2000-10-25

文章信息/Info

Title:
The influence and changes of heart rate variability with obstructive sl eep apnea
作者:
谢文*;  张丙芳**;  戚好文;  林允信　
第四军医大学西京医院呼吸科, 陕西西安710032
Author(s):
XIE Wen; 　ZHANG Bing-fang; 　QI Hao-wen; 　LIN Yun-xin
Department of Respiratory Medicine,Xijing Hospital, Fourth Military Medical University,Xi′an Shaanxi 710032,China
关键词:
睡眠呼吸暂停综合征; 心率变异性; 自主神经系统
Keywords:
sleep apnea syndrome; heart rate variability; autonomic nervo us system
分类号:
R540.41
DOI:
-
文献标识码:
A
摘要:
目的 研究阻塞性睡眠呼吸暂停综合征(OSAS)患者心率变异性(HRV) 的变化。方法 经夜间多导睡眠图(PSG) 7 h监测及动态心电图检查，选取 重 度OSAS患者及正常受试者各20例，采用时域法和频域法分析HRV。结果 OS AS组与对照组比较时域指标SDANN，SDNN，rMSSD显著增高，SDNN-index则显著降低，频域 指标VLF，LF，HF，LFnrom,HFnorm及LF/HF均较对照组显著增 高。结论 OSAS患者交感神经及副交感神经活动均增强，交感神经活动增 强占优势。
Abstract:
AIM To investigate the relation of obstructive sleep apnea syndro me (OSAS) and heart rate variability (HRV). METHODS Twenty patients w ith severe OSAS were recruited to undergo 7-hour polysomnography (PSG) and ECG monitoring in sleep lab,twenty age-matched healthy were studied as controls. Time domain and frequency domain analysis of HRV were performed. RESULTS HRV time domain indices including SDANN,SDNN,rMSSD in OSAS patients were significant ly higher than those in the controls,SDNN-index decreased remarkably. Freguency domain indices including VLF, LF, HF, LFnorm, HFnorm and LF/HF increased significantly compared with the controls. CONCLUSION The sympathetic and parasymp athetic nerve activity were enhanced,the former is prior to the latter.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2000-01-13.
更新日期/Last Update: 2000-10-25