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|本期目录/Table of Contents|

心脏氯离子通道研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第6期
页码:
473-477
栏目:
综述
出版日期:
2000-12-01

文章信息/Info

Title:
-
作者:
张晓东;  臧益民;  周士胜
第四军医大学生理学教研室, 陕西西安, 710032
Author(s):
-
关键词:
阴离子转运;  氯通道;  心脏
Keywords:
-
分类号:
Q25
DOI:
-
文献标识码:
A
摘要:
阴离子转运存在于各种细胞 ,并对细胞功能产生一定影响。在过去 10年中 ,至少在哺乳动物心脏上发现了 6种不同性质的 Cl-通道。本文重点综述近年来心肌 Cl-通道特点、生理作用及在病理状态下的可能作用等方面的研究进展。
Abstract:
-

参考文献/References

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[12]Wang L, Chen L, Jacob TJ. The role of ClC-3 in volume-activated chloride currents and volume regulation in bovine epithelial cells demonstrated by antisense inhibition [J]. J Physiol (Lond) , 2000, 524 (1) : 63.P22

[13] Gandhi R, Elble RC, Gruber AD, et al. Molecular and functional characterization of a calcium-sensitive chloride channel from mouse lung [J]. J Biol Chem, 1998, 273 ( 48) :32096.

[14] Gruber AD, Elble RC, Ji HL , et al. Genomic cloning, molecular characterization, and functional analysis of human CLCA1, the first human member of the family of Ca2+ -activated Cl- channel proteins[J]. Genom ics, 1998, 54 (2) : 200.

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[16] Zygmunt AC, Goodrow RJ , Weigel CM. INa Ca and ICl (Ca) contribute to isoroterenol-induced delayed after depolarizations in midmyocardial cells [J]. Am J Physiol, 1998, 275 (6 P t 2) : H1979.

[17] Hiraoka M , Kawano S, Hirano Y, et al. Role of cardiac chloride currents in changes in action potential characteristics and arrhythmias[J]. Cardiovasc Res, 1998, 40 (1) : 23.

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[19] 周士胜, 王跃民, 董　玲, 等. 92羧酸蒽对豚鼠心室肌动作电位和L型Ca电流的影响[J]. 中国应用生理学杂志, 2000, 16 (1) :22.

[20]Clemo HF, Stambler BS, Baumgarten CM. Swelling-activated chloride current is persistently activated in ventricularmyocytes from dogs with tachycardia-induced congestive heart failure[J]. Circ Res, 1999, 84 (2) : 157.

[21]周士胜, 臧益民: 单羧酸类Cl- 通道阻断剂对心室肌CFTR Cl- 通道的影响[J ]. 生理学报, 1999, 51 (3) : 297.

备注/Memo

备注/Memo:
收稿日期：2000-07-01.
更新日期/Last Update: 2000-12-01