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|本期目录/Table of Contents|

腺苷对心脏作用的机制(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第6期
页码:
478-481
栏目:
综述
出版日期:
2000-12-01

文章信息/Info

Title:
-
作者:
赵正航1 臧伟进1 臧益民2 于晓江1
1.西安医科大学心血管生理药理研究室, 陕西西安710061; 2.第四军医大学生理学教研室
Author(s):
-
关键词:
腺苷 心律失常 受体 腺苷 心脏 膜电流
Keywords:
-
分类号:
R972; R541.7
DOI:
-
文献标识码:
A
摘要:
本文综述了腺苷对心脏的作用及机制, 以及对膜电流的影响。
Abstract:
-

参考文献/References

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[4] Freilich A, Tepper D. Adenosine and its cardiovascular effects [J]. Am Heart J , 1992, 123: 1324.

[5] Martynyuk AE, Morey TE, Belardinelli L, et al. Hyperkalemia enhances the effect of adenosine on Ik.Ado in rabbit isolated AV nodal myocytes and on AV nodal conduction in guinea pig isolated heart [J]. Circulation, 1999, 99: 312.

[6]Martynyuk AE, Kane KA , Cobbe SM, et al. Adenosine increases potassium conductance in isolated rabbit atrioventricular nodal myocytes[J]. Cardiovasc Res, 1995, 30: 668.

[7] Zang WJ , Yu XJ , Honjo H, et al. On the role of G protein activation and phosphorylation in desensitization to acetylcholine in guinea-pig atrial cells[J]. J Physiol, 1993, 464,649.

[8] Martynyuk AE, Kane KA , Cobbe SM, et al. Nitric oxide mediates the anti-adrenergic effect of adenosine on calcium current in isolated rabbit atrioventricular nodal cells [J]. Pfugers Arch Eur J Physiol, 1996, 431: 452.

[9] Han X, Shimoni Y, Giles WR. A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate[J]. J Gen Physiol, 1995, 106: 45.

[10]Shimoni Y, Han X, Severson D, et al. Mediation by nitric oxide of the indirect effects of adenosine on calcium current in rabbit heart pacemaker cells[J]. Br J Pharmacol, 1996, 119: 1463.

[11] Satoh H, Electrophysio logical actions of adenosine and aminophylline in spontaneously beating and voltage-clamped rabbit sinoatrial node preparations [J]. Naunyn Schmiedebergs Arch Pharmacol, 1993, 347: 197.

[12] Zaza A , Rocchetti M , Difranceso D. Modulation of the hyperpolarization-activated current by adenosine in rabbit sinoatrialmyocytes[J]. J Physiol, 1994, 475: 84P.

[13] Henry P, Demolombe S, Puceat M, et al. Adenosine A1 stimulation activates protein kinase C in rat ventricular myocytes[J]. Circ Res, 1996, 78: 161.

[14]Hu K, duan D, Li GR, et al. Protein kinase C activates ATP-sensitive K+ current in human and rabbit ventricular myocytes [J]. Circ Res, 1996, 78: 492.

[15]Li GR, Feng J, shrier A , et al. Contribution of ATP-sensitive potassium channels to the electrophysiological effects of adenosine in guinea-pig atrial cells [J]. J Physiol, 1995, 484:629.

[16] Oe K, Sperlagh B, Santha E, et al. Modulation of norepinephrine release by ATP-dependent K+-channel activators and inhibitors in guinea-pig and human isolated right atrium [J]. Cardiovasc Res, 1999, 43 (1) : 125.

[17] Duan D, Ye L , Britton F, et al. Purinocepter-coupled Cl-channels in mouse heart: a novel, alternative pathway for CFTR regulation[J]. J Physiol (Lond) , 1999, 521 (p t1) : 43.

[18]Cordeiro JM , Ferrier GR, Howlett SE. Effects of adenosine in simulated ischemia and reperfusion in guinea pig ventricular myocytes[J]. Am J Phy siol, 1995, 269: H121.

[19]Wang D, Sh ryock JC, Belardinelli L. Cellular basis for the negative dromotropic effect of adenosine on rabbit single atrioventricular nodal cells[J]. Circ Res, 1996, 78: 697.

[20]Vinten-Johansen J , Thourani VH, Ronson RS, et al. Broad-spectrum cardioprotection with adenosine [J]. Ann Thorac Surg , 1999, 68 (5) : 1942.

[21]Day YJ , Gao Z, Tan PC, et al. ATP sensitive potassium channel and myocardial preconditioning [J]. Acta A naesthesiol Sin, 1999, 37 (3) : 121.[22] Liang BT, Jacobson Ka. Adenosine and ischemic preconditioning[J]. Curr Pharm Des, 1999, 5 (12) : 1029.

备注/Memo

备注/Memo:
收稿日期:2000-03-25.基金项目:国家自然科学基金(No. 39870334,No. 39970273)、国家教委留学回国人员启动基金及世川医学奖学金同学会科研启动基金(No. 025) 资助项目
更新日期/Last Update: 2000-12-01