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多巴酚丁胺负荷试验中冠心病患者左室舒张功能的参数变化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第2期
页码:
106-108
栏目:
论著
出版日期:
2001-03-01

文章信息/Info

Title:
Variation of left ventricular diastolic function indexes in coronary artery disease during dobutamine stress echocardiography
作者:
吴巧英1 ; 钱蕴秋1 ; 张军1 ; 周晓东1 ; 朱永胜1 ; 李楠1 ; 李寰2
第四军医大学西京医院：1．超声诊断科，2 心脏内科，陕西西安710032
Author(s):
WU Qiao-ying1 ; QIAN Yun-qiu1 ; ZHANG Jun1 ; ZHOU Xiao-dong1 ; ZHU Yong-sheng1 ; LI Nan1 ; LI Huan2
1．Department of Ultrasonography, 2．Department of Cardiology，Xijing Hosptial，Fourth Militory Medical University，Xi'an Shaanxi 710032，China
关键词:
多巴酚丁胺负荷试验; 左室舒张功能; 冠状动脉疾病
Keywords:
dobutamine stress test; left ventricuIar diostolic function; coronary disease
分类号:
R540.45
DOI:
-
文献标识码:
A
摘要:
目的 探讨多巴酚丁胺负荷试验中左室舒张功能的参数变化及其在冠心痛诊断中的意义。方法 对l8例正常人和30例冠心病患者进行多巴酚丁胺负荷超声心动图检查，分析比较静息状态与峰值负荷状态下两组左室舒张功能各参数的变化情况。结果 多巴酚丁胺负荷后，两组心率、收缩压均明显增加，组间比较有明显差异；左室舒张早期峰值血流速度(E)和左室舒张早期血流传播速度(RFP)在对照组表现为增加，在冠心病组为减低；冠心病组出现局部室壁运动异常(RWMA)25例，对照组有l例出现RWMA。结论 多巴酚丁胺负荷试验中左室舒张功能的参数变化是反映冠心病心肌缺血的敏感指标，可为冠心病诊断提供有力帮助。
Abstract:
AIM To investigate the variation of left ventricular diastolic function indexes during dobutamine stress echocardiography． METHODS Changes of left ventricular diastolic function indexes were observed in 18 normal subjects and 30 patients with coronary artery stenosis．RESULTS In both groups dobutamine induced similar increases in heart rate and systolic blood pressure; dobutamine caused increases in control subjects and decreases in patients in peak early filling veloclty(E)and rate of flow propagation (RFP);during the test，25 patients had wall motion abnormalities,and ischemia occurred to one of the control subjects．CONCLUSION During dobutamine stress test,an abnormal response of left ventricular diastolic function is a sensitive index for myocardial ischemia and of high value in detecting coronary artery diseases.

参考文献/References

[1]Dagianti A,Penco M,Agati L,et al.Stress echocardiography comparison of exsercise,dipyridamole and dobutamine in detecting and predicting the extent of coronary artery disease [J]．JACC,1995,26(1)：18．

[2]Schablmen SE,Detection of diastolic left ventricular function abnormalities in patient with coronary artery diseese and normal systolic functicn[J]．Clin Cardiol．1983.6(2)：292．

[3]钱蕴秋．超声心动图评价左室舒张功能的新进展[J]．中国超声医学杂志.1999,15(增刊):1．

[4]Giannuzzi P,Imparato A, Tenporelli PL,et al．Doppler derived mitral deceleration time of early filling as a strong predictor of pulmonary capillary wedge pressure in postinfarction patients with left ventricular systolic dystuaction[J]．JACC．1994,23(7):1630．

[5]Tomimoto S,Takenchi M,Fukuzaki H．Noninvasive assessment of left ventrieular diastolic filling in coronary disease by Doppler dipyridamole-stress testing[J]．Jpn Heart J.1989,30(4)：765．

[6]EL-Said MB，Roelandt MD,Paolo M，et al．Abnormal left ventricular early diastolic filing during dobutamine stress Doppler echocardiography is a sensitive indicator of significant coronary artery disease[J]．JACC．1994，24(7):1618．

备注/Memo

备注/Memo:
收稿日期：2000-03-24.
更新日期/Last Update: 2001-03-01