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冠状动脉内支架安置术对细胞粘附分子CD11b 水平的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第4期
页码:
249-250
栏目:
论著
出版日期:
2001-07-01

文章信息/Info

Title:
The clinical sign if icance of the change in the expression level of the cell adhere molecule CD11b with in trocoronary stent
作者:
王海燕;  李　虎;  贾国良;  郭文怡;  李伟杰;  李　飞
第四军医大学西京医院心内科, 陕西西安710032
Author(s):
WANG Hai-yan;  LI Hu;  JIA Guo-liang ;  GUO Wen-yi; LI Wei-jie; LI Fei
Department of cardiology, Xijing Hospital, Fourth Military Medical University, Xi’an Shaanxi 710032, China
关键词:
冠状血管造影术;  支架;  白细胞;  细胞间粘附分子;  CD11b
Keywords:
stent;  coronary angiography;  leukocyte;  cell adhere molecule;  CD11b
分类号:
R541. 4　
DOI:
-
文献标识码:
A
摘要:
目的 观察冠状动脉内支架(ICS) 安置术对患者白细胞表面粘附分子CD11b 水平的影响并讨论其临床意义。方法 将62例冠心病患者分成ICS 组(n=34) 和冠脉造影(CA) 组(n=28)。再将两组患者按AHA/ACC 规定分成A, B, C 3 个亚组。测定两组患者术前和术后15 min 冠状静脉窦血中白细胞表面CD11b 水平。结果 两组术前CD11b 水平无差异, 术后15 min ICS 组的有显著增高; 3 个亚组间术前和术后15 min CD11b 均无显著差异。结论 ICS 可引起白细胞的激活; CD11b 水平和ICS 安置术所致的白细胞活化水平都与病变复杂程度无相关性。
Abstract:
AIM To study the change in the expression level of the leukocyte in the patients undergoing Introcoronary stent ( ICS ) for the purpose of guiding the clinical medication.METHODS There were 62 patients divided into coronary angiography group (n= 28) and ICS group (n=34) , which were further divided into three subgroups according to the lesion types of AHA/ACC. CD11b was measured in all the patients’samples of coronary sinus blood (CSB) ,which were collected at the pre- and 15-m inute- post operations. RESULTS There was no significant difference in the CD11b level between the groups at pre-operations, but it was higher in the ICS group at post operations. There was no significant difference among the three subgroups at the two points. CONCLUSION The leukocyte could be activated in the ICS. But there was no relationship between the lesion types and the degree of the leukocyte act ivated in the ICS, or the CD11b level.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2000-09-20.
更新日期/Last Update: 2001-07-01