我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

血清脂蛋白(a) 水平与冠状动脉狭窄及心绞痛类型的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第6期
页码:
464-466
栏目:
论著
出版日期:
2001-11-01

文章信息/Info

Title:
Correlation of serum Lipoprote in (a) with stenosis of coronary artery and type of angina pectoris
作者:
刘松岩;  杨欣国;  侯允天
第四军医大学唐都医院心内科, 陕西西安710038
Author(s):
LIU Song-yan;  YANG Xin-guo;  HOU Yun-tian
Department of Cardiology, Tangdu Hospital, Fourth Military Medical University, Xi’an Shaanxi 710038, China
关键词:
刘松岩;  杨欣国;  侯允天
Keywords:
atherosclerosis;  coronary artery stenosis;  angina pectoris;  Lipoproteins
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨血清脂蛋白(a) [Lp(a)]与冠状动脉狭窄程度及心绞痛类型的关系。方法 将91 例冠脉造影患者按狭窄程度分组, 比较各组血清Lp(a) , C 反应蛋白及血脂指标等, 并对其中76 例按心绞痛分2 组, 也进行同样的比较, 均进行统计学分析。结果 血清Lp(a) 水平在冠脉明显狭窄以及多支血管病变患者显著升高, 不稳定心绞痛患者的血清Lp(a) 水平也明显高于稳定型心绞痛患者(P < 0. 01) ,Lp(a) 异常率在冠脉造影阴性与冠脉造影阳性患者中 有明显差异, 不稳定型心绞痛患者的Lp(a) 异常率所占比例较稳定型患者高(77% vs 51% , P < 0. 01)。结论 Lp(a) 水平与冠脉狭窄程度和心绞痛类型明确相关。
Abstract:
AIM To demonstrate the correlation of serum Lipoprotein (a) [Lp(a) ] with stenosis of coronary artery and type of angina pectoris. METHODS 91 patients with angiographic findings were divided to 3 groups and 76 of 91 patients with angina pectoris to two groups and their blood specimen were analyzed for Lp(a) and C-reactive protein, etc. RESULTS There was a singnificant trend of increasing Lp(a) levels compared with the degree and multiple vessels of coronary stenosis. The rate of abnormal Lp(a ) in patients with severe coronary stenosis was higher than that of normal coronary artery. The levels of Lp(a) in patients of with unstable angina were significantly higher than that of stable angina, and the rate of abnormal Lp(a) in patients with un stable angina was higher too (77% vs 51% , P < 0. 01). CONCLUSION Serum Lp(a) level correlated with the degree of coronary stenosis and with different type of angina pectoris.

参考文献/References

[1] Dahlen GH. lipoprotein (a) in cardiovascular disease [J].Atherosclerosis, 1994, 108: 111.

[2] Niendorf A , Rath M , Wolf K, et al. Morphological detection and quantification of lipoprotein (a) deposition in atheromatous lesions of human aorta and coronary arteries [J]. Virchows Arch, 1990, 417: 105.

[3] Rhoads GG, Danlen GH, Berg K, et al. Lp(a) lipoprotein is a risk factor for myocardial infarction [J]. JAMA , 1986, 256:2540.

[4] Desmarais RL , Sarembocd IJ , Ayers CR, et al. Elevated serum lipoprotein (a) is a risk factor for clinical recurrence after coronary balloon angioplasty [J]. Circulation, 1995, 91: 1403.

[5] Kronberg F, Steinmetz A , Kostner GM. Lipoprotein (a) in health and disease[J]. Crit Rev Clin Lab Sci, 1996, 33: 459.

[6] Lawn RM , Scanu AM. Lipoprotein (a) [A]. Fuster V , Ross R,Topol EJ. Atherosclerosis and coronary disease[M]. Philabel-phia: Lippicott-Raven Pub, 1996. 151.

[7] Dangas G, Mehran R, Harpel PC, et al. Lipoprotein (a) and inflammation in human coronary atheroma: association with the severity of clinical presentation [J]. J Am Coll Cardiol, 1998,32 (7) : 2035.

备注/Memo

备注/Memo:
收稿日期：2000-07-21.
更新日期/Last Update: 2001-11-01