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心血管病患者幽门螺杆菌感染与血脂、一氧化氮水平的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第2期
页码:
134-135,138
栏目:
临床研究
出版日期:
2002-03-01

文章信息/Info

Title:
Relation of hepicobacter pylori infection with the levels of lipids and nitric oxide in patients with cardiovascular diseases
作者:
陈良海;  李　刚;  李代渝;  刘远厚;  罗兴林;  薛　莉
泸州医学院附属医院心内科, 四川 泸州 646000
Author(s):
CHEN Liang-hai; LI Gang ; LI Dai-yu; LIU Yuan-hou; LUO Xing-lin;  XUE Li
Department of Cardiology, Affiliated Hospital, Luzhou Medical College,Luzhou Sichuan 646000, China
关键词:
心血管疾病;  螺杆菌;  幽门;  螺杆菌感染;  血脂;  一氧化氮
Keywords:
cardiovascular diseases;  helicobacter pylori;  helicobacter infections;  lipid;  nitric oxide
分类号:
R543; R378　
DOI:
-
文献标识码:
A
摘要:
目的 探讨幽门螺杆菌(HP)感染与血脂、一氧化氮(NO)水平的关系。方法 测定心血管疾病患者192例的血清HPIgG、总胆固醇(TC)、甘油三脂(TG)、载脂蛋白A1 (ApoA1)、载脂蛋白B(ApoB)、脂蛋白a[Lp(a)]、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、一氧化氮(NO)、一氧化氮合酶(NOS)的含量。结果 HP感染108例,HP感染组的血清TG,ApoB,NOs,NO浓度较未感染组明显升高(P<0.05) , TC,Lp(a) ,LDL2C 有增高趋势, 但未达显著水平. 结论 HP感染可明显升高血清TG,ApoB,NOS,NO的含量。
Abstract:
AIM To determine the relation of helicobacter pylori (HP) infection with the levels of lipids and nitric oxide (NO). METHODS Serum specific IgG antibodies to HP (HPIgG) and serum levels of total cholesterol (TC) , triglyceride (TG) , apolipoprotein A1 (ApoA1) , apolipoprotein B(ApoB) , apolipoprotein (a) [Lp(a) ], high density apolipoprotein cholesterol (HDL-C) ,Low density apolipoprotein cholesterol (LDL-C) ,NO and nitric oxide synthase (NOS) were measured in 192 patients with cardiovascular diseases. RESULTS 108 patients were infected by HP. The levels of serum TG,ApoB,NO ,NOS in the cases of HP seropositivity were significantly higher than those in the cases of HP seronegativity (P < 0. 05). The levels of TC,Lp (a) ,LDL-C, tended to be higher in those who were HP positive than in those who were HP negative, but the trend was non-significant. CONCLUSION HP infection might increasethe lipids and NO.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2000-11-07.
更新日期/Last Update: 2002-03-01