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|本期目录/Table of Contents|

经皮冠状动脉腔内成形术前后冠心病患者血清C反应蛋白的变化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第3期
页码:
219-220
栏目:
临床研究
出版日期:
2002-05-01

文章信息/Info

Title:
The changes of serum C-reactive protein of coronary heart disease patients before and after PTCA
作者:
闫韵洪;  张利华
第四军医大学唐都医院心内科, 陕西 西安 710038
Author(s):
YAN Yun-hong ;  ZHANG Li-hua
Department of Cardiology, Tangdu Hospital, Fourth Military Medical University, Xi’an, Shaanxi 710038, China
关键词:
血管成形术;  经腔;  经皮冠状动脉;  冠状动脉疾病;  C 反应蛋白
Keywords:
angioplasty;  transluminal;  percutaneous coronary;  coronary disease;  C-reactive protein
分类号:
R543.3
DOI:
-
文献标识码:
A
摘要:
目的 观测经皮腔内冠状动脉成形术(PTCA ) 对血清C 反应蛋白(CRP) 的影响。方法 我院进行PTCA 的患者86 例, 同期进行冠状动脉造影(CAG) 的患者60 例。分别于PTCA 和CAG 当天及术后第二天清晨采集空腹血测定CRP 值。结果 PTCA 组术后血清CRP 水平显著高于术前(P<0.01) , CAG 组造影后血清CRP 水平与造影前比较无显著性差别(P>0.05)。结论 PTCA 明显增加血清CRP 浓度, 可能与PTCA 治疗后局部血管炎症有关。
Abstract:
AIM To examine the effect of percutaneous transluminal coronary angioplasty(PTCA) on serum levels of C-reactive protein(CRP).METHODS 86 patients who underwent PTCA were included in this study, and 60 patients who received coronary angiography (CAG)during the same period were selected as controls. Serum samples for measurement of CRP were taken in the early morning of the procedure and the followed early morning after the procedure.RESULTS In patients with PTCA,CRP levels after the procedure were significantly higher than that before the procedure (P<0.01). In CAG group, CRP levels after angiography were not significantly higher than that before angiography (P>0.05).CONCLUSION PTCA leads to a detectable increase in serum levels of CRP,which is probably related with the intrinsic inflammation or tissue damage within arterial lesions treated with PTCA.

参考文献/References

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[3] Tataru MC,Heinrich J,Junker R,et al. C-reactive protein and the severity of atherosclerosis in myocardial infarction patients with stable angina pectoris[J].Eur Heart J,2000,21(12):1000-1008.

[4] Masami K,Kazuo K,Toshiyuki L,et al. Relation between C-reactive protein levels on admission and pattern of acute myocardial infraction onset[J].Am J Cardiol,2000,86(1):83-86.

[5] Morrow DA,Rifain W,Antman EM,et al. C-reactive protein is a potent predictor of mortality independently of and combination with troponin T in acute coronary syndromes: a TIMI IIA substudy[J].J Am Coll Cardiol,1998,31:1460-1464.

备注/Memo

备注/Memo:
收稿日期：2001-09-18.
更新日期/Last Update: 2005-05-01