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|本期目录/Table of Contents|

先倍领对大鼠微循环和血液流变学的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第3期
页码:
233-235
栏目:
实验研究
出版日期:
2003-05-01

文章信息/Info

Title:
The effects of hemorheology and microcirculation on rat model of blood stasis syndrome on the xianbeiling
作者:
唐荔; 石小鹏; 郭凤伟; 沈敏; 戴甜甜
第四军医大学西京医院药剂科,陕西 西安710032
Author(s):
TANG Li; SHIXiao-peng; GUOFeng-wei; SHEN Min; DAITian-tian
Department of Medicament,XijingHospital,Fourth Military Medical University,Xi’an, Shaanxi710032, China
关键词:
先倍领注射液; 流变学特性; 微循环; 血瘀症
Keywords:
xianbeiling; hemorheology; microcirculation; blood stasis syndrome
分类号:
R912
DOI:
-
文献标识码:
A
摘要:
目的:观察先倍领对血瘀大鼠微循环和血液流变学特性的影响。方法:SD大鼠30只,随机分为空白组、模型组和实验组,在连续14d中,实验组大鼠肌注先倍领注射液(0.25ml·kg-1),在第13天,将实验组和模型组大鼠皮下注射肾上腺素(0.07ml·kg-1)和冰水刺激造成大鼠急性血瘀模型,观察大鼠肠系膜微循环及血液流变学指标;空白组和模型组给予同样体积的生理盐水。结果:先倍领与模型组相比,在微循环各指标中均存在显著性差异(P<0.01),在血液流变学各指标中也存在显著性差异(P<0.05或P<0.01)。结论:先倍领对大鼠的血瘀症状有明显的缓解作用。
Abstract:
AIM:To observe the effects of hemorheology and microcirculation on rat model of blood stasis syndrome on the xianbeiling.METHODS:In the 14 days,The rat was administered continuously the xianbeiling by im(0.25ml·kg-1).At the 13d,the rat of both the experiment group and model group were made the model of blood stasis syndrome by ip adrenalin(0.07ml·kg-1)and the stimulation of ice-water,to observe the microcirculation of mesentery and determine the index of hemorheology;the same bulk of NS was administered in controll,the same bulk of PASS was iv in model.RESULTS:Comparing the model,the xianbeiling can markedly improve the index of the hemorheology and microcirculation(P<0.05orP<0.01).CONCLUSION:The xianbeiling has the ability of improvement on the rat of blood stasis syndrome.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2002-10-22.
更新日期/Last Update: 2003-05-01