我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

次声作用后大鼠下丘脑血管紧张素Ⅱ含量的改变(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第4期
页码:
293-295,299
栏目:
实验研究
出版日期:
2003-07-01

文章信息/Info

Title:
Change of angiotensin Ⅱ in hypothalamus of rats exposed to infrasoun
作者:
赵志刚; 陈景藻; 张李燕
第四军医大学预防医学系放射医学教研室,陕西 西安 710032
Author(s):
ZHAO Zhi-gang;  CHEN Jing-zao;  ZHANG Li-yan
Department of Radiation Medicine, Faculty of Preventive Medicine, Fourth Military Medical University, Xi'an, Shaanxi 710032, China
关键词:
次声; 大鼠; 下丘脑; 血管紧张素Ⅱ
Keywords:
infrasound;  rat;  hypothalamus;  angiotensin Ⅱ
分类号:
R394
DOI:
-
文献标识码:
A
摘要:
目的:观察次声作用后大鼠下丘脑血管紧张素Ⅱ(AngⅡ)含量的变化。方法:用16Hz,(130dB和90dB)次声连续作用1,7,14,21次,2h/次。每月1次。分别于作用后0.5,6,12,18,24h观察大鼠下丘脑AngⅡ含量。结果:130dB次声作用1,14,21次和90dB次声作用7,21次后,大鼠下丘脑AngⅡ含量均经历升高,下降,复呈升高的动态变化过程。130dB次声作用7次后大鼠下丘脑AngⅡ含量呈持续性升高。90dB次声作用1,14次后,大鼠下丘脑AngⅡ含量呈升高和下降的单峰曲线,且14次组于次声停止作用后12h已与对照组之间的差异无显著性意义。结论:不同声强和作用次数的次声,对大鼠下丘脑AngⅡ含量的影响呈波动性改变。
Abstract:
AIM: To observe the change of angiotensin Ⅱ (AngⅡ) in hypothalamus of rats exposed to infrasound. METHODS: The rats were exposed to infrasounds (frequence: 16Hz;acotustic pressure: 130dB and 90dB),for 1, 7, 14, and 21d, 2h daily, then AngⅡ contents were measured 0.5, 6, 12, 18, and 24h after the exposure. RESULTS: AngⅡ varied regularly, increasing firstly, then decreasing, and increasing again, after rats exposed to infrasound either with 130dB for1, 14 and 21dor with 90dB for 7 and 21d. In rats exposed to infrasound with 130dB for 7d AngⅡ increased continuously. After the exposure to infrasound with 90dB for 1 and 14d, AngⅡ of rats presented on the peak curve, and 12h after the group were exposed to infrasound for 14d, no signficant difference was detected between the exposure and the control groups. CONCLUSION: The content of AngⅡ in the hypothalamus of rats affected by the infrasounds with different sound intensities and by different numbers of exposures was fluctuated.

参考文献/References

[1] 杨钢, 席正雄, 万喻, 等. 应激时大鼠血、脑、心血管、肾上腺AngⅡ含量的变化 [J] . 生理学报, 1993, 45(5):505-507.

[2] 梁之彦. 生理化学 [M] . 上海:上海科学技术出版社, 1990. 657-673.

[3] Iwai N. Indentification of two subtypes in the rat type I angiotensinⅡ receptor [J] . FEBS, 1992, 298(2-3):257-260.

[4] 4]БaтaHoBГB. OcoбeHHocтИ φopMИpoBaHИЯ ΓИπep<=Bcт-BИтe>?HocтИ HeMe@>eHHoΓo тИπa B =c>oBИЯA BoB@eCcтBИЯ Ha opΓaHИBM ИHφpaBB=Da [J] . Ea@ИaFИoHHaЯ бИo>oΓИЯИ Ea@ИoGDo>oΓИЯ , 1995,35(1):78-82.

备注/Memo

备注/Memo:
收稿日期：2002-05-07.
更新日期/Last Update: 2003-07-01