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冠状动脉病变早期临床诊断的多因素分析(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第4期
页码:
333-335
栏目:
临床研究
出版日期:
2003-07-01

文章信息/Info

Title:
The multiple factor analysis of clinical diagnosis in patients with early coronary heart disease
作者:
李海斌1; 陈士良2; 李志樑1
1.第一军医大学珠江医院心内科,广东 广州 510280;2.解放军305医院心内科,北京 100017
Author(s):
LI Hai-bin1;  CHEN Shi-liang1; LI Zhi-liang2
1.Department of Cardiology, Zujiang Hospital, First Military Medical University, Guangzhou Guangdong 510282, China;2.Department of Cardiology, 305 Hospital of PLA, Beijing 100017,China
关键词:
冠状动脉疾病; 冠状动脉造影术; 心电描记术
Keywords:
coronary disease;  coronary angiography;  electrocardiography
分类号:
R540.4
DOI:
-
文献标识码:
A
摘要:
目的:评估各种方法对冠心病早期诊断的价值,探索早期冠心病的独立预报因子。方法:收集46例经冠状动脉造影确定的冠心病患者症状、静息心电图和常规临床检查等相关信息进行统计学分析。结果:冠状动脉造影21例正常(正常组),25例出现冠状动脉狭窄(冠心病组),平均狭窄程度为(46±15)%。比较两组的一般情况、临床症状、甘油三酯、胆固醇、低密度脂蛋白、负荷心电图、放射线及心脏超声等项目,各项指标无显著差异,Logistic回归显示这些因素对冠心病的早期诊断无预测意义。结论:冠心病患者的早期病变以临床常规各项方法难以准确检测和预报,冠状动脉造影是确诊冠心病者早期病变的最佳方法。
Abstract:
AIM: To evaluate the utility of the common diagnostic examinations in patients with early coronary heart disease (CHD). METHODS: Forty-six patients with a typical clinical situation of CHD and normal resting electrocardiogram (ECG) experienced loading ECG, serum examination and X-radial telegraphy, and underwent coronary angiography (CAG). Then, identify the independent factor to CHD from these indexes by using Logistic regression. RESULTS: Patients were categorized into two groups based on the results of the arteriongraphy: control (21 cases) without artery stenosis and CHD (25 cases) with a mean artery stenosis of (46±15)%. Age, sex, blood pressure, clinical situation, serum triglycerides, serum cholesterol, serum low density lipoprotein, loading ECG, X-radial telegraphy, and ultrasonography of the heart were compared between the CHD and the control groups, and it was found that there was not any significant difference between the two groups. Logistic model showed that none of the above factors was an independent predictor to early CHD. CONCLUSION: The above routine non-invasive examinations help little in diagnosing early CHD, so it is suggested that CAG is a golden way early CHD can be diagnosed exactly.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2002-02-20.
更新日期/Last Update: 2003-07-01