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|本期目录/Table of Contents|

影响法洛四联症患者存活的因素(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2004年第4期
页码:
359
栏目:
临床研究
出版日期:
2004-07-01

文章信息/Info

Title:
Analysis of survival factor in the patients with tetralogy of Fallot
作者:
朱鲜阳王淑范张玉威韩秀歌邓东安全筱盛晓案王琦光金岩
解放军心血管内外科研究所,沈阳军区总医院先心病内科,辽宁沈阳11001
Author(s):
ZHU Xian-yang WANG Shu-fanZHANG Yu-wei HAN Xiu-minDENG Dong-anQUAN WeiSHENG Xiao-tang WANG Qi-guang JIN Yan
Department of Congenital Heart Disease Internal Medicine,Cardiovascular Institute of PLA&General Hospital of Shenyang Military Army, Shenyang,Liaoning 110016,China
关键词:
法洛四联症儿童成人存活因素
Keywords:
tetralogy of Fallotchildadultsurvival facto
分类号:
R541.1
DOI:
-
文献标识码:
A
摘要:
目的:分析影响法洛四联症患者存活的因素。方法:对2134例法洛四联症患者的资料进行回顾性分析.根据住院时年龄分儿童组和成人组,成人组(>15岁)460例,儿童组(<15岁)1674例。通过症状、体征、X线胸片、心电图、超声心动图和心血管造影资料分析,观察其临床表现特点.结果:经统计学处理发现低载发作、右室流出道狭窄的严重程度、左心室发育不良和并存的其它心脏崎形的发生率,儿童组显著高于成人组(P<0. 01),而肺动脉瓣下 室缺的发生率,成人组则显著商于儿童组(P<0. 01).结论:低载发作,右室流出道狭窄的范围及程度,室缺位置,左室大小和并存畸形是影响法洛四联症患者存活的主要因素。
Abstract:
AIM:To assess the clinical manifestation and survival factors in the patients with tetralogy of Fallot. METHODS:2134 patients were reviewed retrospectively. They were divided into two groups based on the admission ages :one consisting of 460 adults aged >=15 years old and the other,1674 children aged <15 years old. The symptoms,physical signs,chest X rays,electrocardiograms, echocardiograms,and the cardioangiography features were analyzed and compared between the children and the adults. RESULTS: The incidences of the hypoxia spells,the severity degree of right ventricular outflow obstruction, the left ventricle dysplasia and other malformation accompanied were more markedly increased in the children than in the adults (P<0.01 ).T hei ncidenceo fv entriculars eptald efectso fin frap ulmonaryv alvei nt hea dultsw ass ignificantly higher than that in the children (P<0. 01).CONCLUSION:The hypoxia spells,the ranges and degree of right ventricular outflow obstruction, the position of ventricular septal defects,the left ventricular dimension and the accompanied malformation were main influence factors in the survival of patients with Tetralogy of Fallot.

参考文献/References

[1] Abraham KA, Cherian G,Rao VD, et al. Tetralogy of Fallot in adults : A report on 147 patients[J].Am J Med,1979,66:811一 816 .

[2] Tucker BL, Lindesmith GG, Takahashi M. Obstructive lesions of the right heart[ M].Baltimore,University Park Press,1984 . 16 一 21.

[3〕布郎瓦尔德(Braunwald E)主编.心脏病学〔M].第五版.北京:人民卫生出版社,2000.842-844.

[4〕张玉威,朱鲜阳,邓东安,等.法洛四联症低氧发作的防治〔J]. 中国循环杂志,1998,13:293-295.

[5] Hggins CB, Mulder DG. Tetralogy of Fallot in the adult[J].Am J Cardiol,1972,29:837一845.

[6] Benge W, White CW. Systemic hypertension complicating Tetralogy of Fallot:effects of antihypertensiye therapy[J].Am J cardiol,1978,42,295一298.

[7]Marelli AJ,Perloff JK,Child JS,et al .Pulmonary atresia with ventricular septal defect in adults[J].Circulation,1994,89:243一 251 .

备注/Memo

备注/Memo:
收稿日期:2003-6-30
更新日期/Last Update: 2004-07-01