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|本期目录/Table of Contents|

EBT检测对冠脉病变危险因素的价值(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2005年第4期
页码:
380-382
栏目:
临床研究
出版日期:
2005-09-05

文章信息/Info

Title:
Risk assessment of coronary artery damage by Electronbeam tomography
作者:
黄晨1; 高建苑1; 吴利平1; 王晓明1; 苏慧1; 郑敏文2
第四军医大学西京医院:1.老年病二科，2.放射科，陕西 西安，710032
Author(s):
HUANG Chen1;  GAO Jianyuan1;  WU Liping1;  WANG Xiaoming1;  SU Hui1;  ZHENG Minwen2
1.Department of Geriatrics, 2. Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, China
关键词:
冠状动脉疾病; 危险性分析; 冠脉钙化; 糖尿病
Keywords:
coronary disease; risk assessment;  coronary artery damage; diabets mellitus
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 应用电子束CT（EBT）心脏扫描，了解受检者冠脉病变的发生情况,分析冠脉病变发生的危险因素。方法 107例受试者行心脏EBT扫描，计算冠脉钙化发生率、钙化积分、冠脉狭窄支数和软斑数，同时收集血糖、糖化血红蛋白（HbA1c）、血脂等相关临床信息, 进行冠脉病变危险因素的分析。结果 糖耐量受损组、糖尿病组、高血压病组冠脉钙化发生率较正常对照组显著升高（93%, 96%， 90% vs 56%, P<0.01）。钙化积分有明显升高趋势, 但统计学检验无显著性差异。冠脉狭窄支数和软斑数显著增加（2.2±2.0， 3.0±1.9，2.2±1.1 vs 0.5±1.3，P<0.05 和 2.5±2.4, 2.9±1.8, 2.3±1.8 vs 0.5±1.2, P<0.05） 。Logistic回归分析，发现糖尿病、高血压两因素对冠脉病变的影响有统计学意义（P<0.05），OR值分别为7.514(95%可信区间0.885 ~ 63.778)、6.653(95%可信区间1.344~32.928)。结论 糖尿病、高血压病患者发生冠脉病变有高度的危险性。
Abstract:
AIM To assess the risk of coronary artery damage by electron beam tomography(EBT) in population. METHODS A total of 107 subjects aged 36~78 years underwent cardiac EBT, with coronary artery calcification(CAC) incidence, calcium scoring, stenosed arteries and soft plaques calculated. Laboratory evaluation included measurement of 75 g oral glucose tolerance test (OGTT), HbA1c, triglyceride, total cholesterol. Logistic regression analysis was taken to assess the risk for coronary artery damage. RESULTS The incidences of CAC in IGT(93%), diabetes(96%) and hypertension (90%) groups were significantly (P<0.01 ) higher than that in the normal(56%). The scores of CAC in IGT, diabetes and CHD groups were also higher though they did not quite reach statistical significance because of our cohort size. The numbers of stenosed arteries and soft plaques were more than those in the normal(2.2±2.0， 3.0±1.9， 2.2±1.1 vs 0.5±1.3，P<0.05 and 2.5±2.4, 2.9±1.8, 2.3±1.8 vs 0.5±1.2, P<0.05). The result of logistic regression analysis: OR of diabetes group was 7.514(95%CI:0.885 ~63.778) and OR of hypertension group was 6.653(95% CI: 1.344~32.928). CONCLUSION The diabetes and hypertension patients have higher risk for coronary artery damage.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2004-09-27.
更新日期/Last Update: 2010-01-05