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Title:: Relationship between insulin-like growth factor I and metabolic syndrome

作者:: 应小盈; 王长谦; 何奔; 上海第二医科大学附属仁济医院心内科，上海 200001

Author(s):: YING Xiao-ying; WANG Chang-qian; HE Ben; Department of Cardiology, Renji Hospital Affiliated to Shanghai Second Medical University, Shanghai 200001, China

关键词:: 代谢综合征; 胰岛素抵抗; 胰岛素样生长因子-I; 体质量指数

Keywords:: metabolic syndrome; nsulin resistance; insulinlike growth factor I; body mass index

分类号:: R442.8

DOI:: -

文献标识码:: A

摘要:: 目的为了研究血清胰岛素样生长因子-I（IGF-I）与代谢综合征、胰岛素抵抗和高胰岛素血症之间的关系。方法本研究分析了75名住院患者冠脉造影结果、代谢综合征的相关情况和血清IGF-I的浓度。结果代谢综合征患者的血清IGF-I水平明显低于非代谢综合征患者，且血清IGF-I水平与血清胆固醇，体质量指数呈负相关，并且在非糖尿病患者中，IGF-I值与HOMA 胰岛素抵抗指数有相关性。结论血清IGF-I水平与胰岛素抵抗有关，与反映胰岛素抵抗的指标如体内脂肪含量和脂代谢紊乱具有相关性。

Abstract:: AIM To explore the relationship between serum insulinlike growth factor I (IGFI) and metabolic syndrome (MS), insulin resistance and hyperinsulinemia. METHODS The coronary artery angiography, MS and serum IGFI level of 75 inpatients. RESULTS The serum IGFI level was much lower in the patients with MS than that in nonMS patients. There was a negative relationship between serum IGF1 and total cholesterol (TC) and body mass index (BMI),in addition it was somewhat related with HOMA insulin resistance index in nondiabetes patients. CONCLUSION serum IGFI is associated with insulin resistance, some dislipidemia and BMI.

参考文献/References

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胰岛素样生长因子-I与代谢综合征及胰岛素抵抗的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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