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16层螺旋CT判别冠状动脉斑块的性质及其临床意义(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第6期
页码:
694-696
栏目:
临床研究
出版日期:
2006-12-25

文章信息/Info

Title:
16-slice spiral computed tomographic coronary angiography in identifying coronary plaque
作者:
杨志明1李海文1康玉明23肖传实1
山西医科大学:1.第二医院心内科, 2.生理学教研室, 山西 太原 030001;3.美国爱荷华大学心内科, 美国爱荷华市, 52242
Author(s):
YANG Zhi-ming1 LI Hai-wen1 KANG Yu-ming23 XIAO Chuan-shi1
1.Department of Cardiology,Second Hospital, 2.Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi 030001; 3.Department of Cardiology, University of Iowa, Iowa City, IA, 52242, USA
关键词:
冠状动脉疾病16层螺旋CT 冠状动脉造影
Keywords:
coronary disease16-slice spiral computed tomography coronary angiography
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 比较16层螺旋CT冠状动脉成像对冠状动脉造影确诊的两个类型冠心病患者冠状动脉斑块类型分布,并探讨其临床意义。方法 将60例住院冠心病患者(均经冠状动脉造影证实为冠心病),据临床诊断分为稳定型心绞痛组(SAP)24 例、急性冠脉综合征组(ACS)36 例,行16层螺旋CT冠状动脉成像,根据螺旋CT值分为软斑块、混合斑块、硬斑块,分析各种不同性质的斑块在两个类型冠心病组的分布。结果 两个类型冠心病组斑块类型的分布存在显著性差异(P<0.05),急性冠脉综合征组以软斑块为主(占50%),混合斑块次之(31%);而稳定型心绞痛组则以硬斑块为主(占62%)。结论 16层螺旋CT冠脉成像可较准确地显示斑块性质,结合冠心病临床分型对冠状动脉斑块稳定性的判别有一定临床价值。
Abstract:
AIM To evaluate coronary plaque using 16slice spiral computed tomography (CT) angiography in patients with coronary heart disease(CHD)confirmed by coronary angiography. METHODS Sixty patients with CHD were confirmed by coronary angiography and divided into stable angina pectoris (SAP, n=24) and acute coronary syndrome (ACS, n=36) groups based on the clinic diagnosis. All the patients underwent 16slice spiral CT coronary angiography to quantify the coronary plaque and then were divided into soft plaque (n=24), mixed plaque (n=14) and hard plaque (n=22) groups based on the CT scale. RESULTS Soft plaque and mixed plaque in the ACS group were more than those in the SAP group (soft plaque: 18 vs 6 cases, ACS vs SAP, P<0.05; mixed plaque: 11 vs 3 cases, ACS vs SAP, P<0.05) and hard plaque in the SAP group was more than that in the ACS group (15 vs 7 cases, SAP vs ACS, P<0.05). CONCLUSION 16-slice spiral CT can be used to assess coronary plaque with high accuracy and together with clinical type of CHD it can also be used to evaluate the stability of coronary plaques.

参考文献/References

[1] Ohnesorge B, Flohr T, Becker C, et al. Cordiac imaging by means of electroncardiographically gated multisection spiral CT: initial experience[J]. Radiology, 2000,217(2):564-571.

[2] Maseri A.Inflammation,atherosclerosis,and ischemic events exploring the hidden side of the moon [J]. N EngI J Med,1997,336(14):1014-1016.

[3] Casscells W,Naghavi M,Willerson JT.Vulnerable atherosclerotic plaque:a multifocal disease[J]. Circulation,2003,107(16):2072-2075.

[4] Fayad ZA.Fuster V.Clinical imaging of the high risk or vulnerable atherosclerotic plaque[J]. Circ Res,2001,89(4):305-316.

[5] 李海文,杨志明. 冠状动脉粥样硬化斑块稳定性鉴别的研究进展[J].心血管病学进展,2005,26(6):581-585.

[6] Schroeder S, Flohr T, Kopp AF, et al. Accuracy of density measure by multislice CT:results of a phantom study[J]. J Comput Assist Tomogr, 2001, 25(6): 900-906.

[7] Estes JM,Quist WC,Lo Gerfo FW,et al. Noninvasive characterization of plaques morphology using helical computed tomography[J]. J Cardiovasc Surg(Torino),1998.39(5):537-534.

[8] Kopp AF, Schroeder S, Baumbach A, et al. Noninvasive characterization of coronary lesion morphology and composition by multislice:first results in comparison with intracoronary ultrasound[J]. Eur Radiol,2001, 11(9):1607-1611.

[9] Schroeder S. Kopp AF,Baumbach A,et al. Noninvasive detection and evalution of atherosclerotic coronary plaques with multislice computed tomography[J]. J Am Coll Cardiol,2001,37(5):1430-1435.

[10]Fayad ZA,Fuster V,Nikolaou K,et al. Computed tomograpy and magnetic resonance imaging for nonoinvasive coronary angiography and plaque imaging:current and potential future concepts[J]. Circulation, 2002, 106(15):2026-2034.

备注/Memo

备注/Memo:
收稿日期:2005-10-10.通讯作者:杨志明,硕士,主任医师,主要从事冠心病的基础及临床研究 Tel:(0351)3365536 Email:Zhimingang800@sina.com
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