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老年阻塞性睡眠呼吸暂停低通气综合征患者血压及心率变异性分析

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第6期
页码:
841-843,850
栏目:
临床研究
出版日期:
2009-11-05

文章信息/Info

Title:
Analysis of blood pressure and heart rate variability in elderly patients with obstructive sleep apnea-hypopnea syndrome
作者:
任春霖1; 胡胜利2; 陈志勇3
1.郧阳医学院附属东风总医院心内科,湖北 十堰 442008；2.福建医科大学附属 第一医院神经外科，福建 福州 350004；3.房县中医院，湖北 十堰 442100
Author(s):
REN Chun-lin1;  HU Sheng-li2;  CHEN Zhi-yong3
1.Department of Cardiology, Dongfeng General Hospital, Yunyang Medical College, Shiyan 442008, Hubei, China; 2.Department of Neurosurgery, First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, Fujian, China; 3.Fang County Traditional Chinese Medical Hospital, Shiyan 442001, Hubei, China
关键词:
老年人; 阻塞性睡眠呼吸暂停低通气综合征; 血压变异性; 心率变异性
Keywords:
eldery subjects;  obstructive sleep apnea-hypopnea syndrome;  blood pressure variability;  heart rate variability
分类号:
R56；R541.7
DOI:
-
文献标识码:
A
摘要:
目的: 探讨老年阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者血压及心率变异性各指标的关系。方法: 2006年1月~2007年12月在我院就诊，经便携式睡眠分析仪（PSG）诊断为老年OSAHS患者41例作为阳性组，因睡觉打鼾就诊并经PSG整夜检测排除OSAHS的老年患者41例作为对照组，进行动态心电图及动态血压检测，计算血压、心率变异性各指标值。结果: 老年OSAHS患者在体质量指数、腰围、颈围等均明显高于对照组（P<0.05或P<0.01）；心率变异性在时域指标SDNN、SDNNI、rMSSD、PNN50及频域指标的TP、LF、HF、LF/HF上与对照组比较差异均有统计学意义（P<0.05）；白天、夜间及24 h收缩压、舒张压血压变异性与对照组比较差异有统计学意义（P<0.05 或P<0.01）。结论: 老年OSAHS患者心率变异性明显异常，血压变异性明显升高。
Abstract:
AIM: To explore the correlation between blood pressure (BP) and heart rate variability (HRV) in elderly patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). METHODS: Included in the study were 41 elderly patients diagnosed with OSAHS (trial group) and 41 elderly snoring patients without OSAHS (control group) by portable polysomnography in our hospital from January 2006 to December 2007. Indexes of BP and HRV of all patients were acquired by Holter and ambulatory blood pressure monitoring. RESULTS: Body mass index, waist circumference and neck circumference in the trial group were significantly higher than those in the control group (P<0.05 or P<0.01). Statistically significant HRV differences were observed between groups in time-domain indexes SDNN, SDNNI, rMSSD and PNN50 as well as frequency-domain indexes TP, LF, HF and LF/HF (P<0.05). Differences of BP variability during day, night, and 24-h systolic and diastolic BP between groups were also statistically significant (P<0.05 or P<0.01). CONCLUSION: HRV of elderly OSAHS patients is significantly abnormal and their BP variability increases significantly, especially at night.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2008-12-3.作者简介：任春霖，副主任技师Email:rcl640318@126.com
更新日期/Last Update: 2009-09-30