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|本期目录/Table of Contents|

非顺应性球囊后扩张对冠状动脉药物洗脱支架植入后支架内亚急性血栓的影响

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第5期
页码:
702-704
栏目:
临床研究
出版日期:
2010-06-22

文章信息/Info

Title:
Influence of postdilatation with noncompliance balloon on subacute thrombosis after intracoronary drug-eluting stent implantation
作者:
周圣华; 卢才义; 张玉霄; 薛桥; 颜伟; 高磊; 翟金月
解放军总医院老年心血管病研究所，北京 100853
Author(s):
ZHOU Sheng-hua;  LU Cai-yi;  ZHANG Yu-xiao;  XUE Qiao; YAN Wei;  GAO Lei;  ZHAI Jin-yue
Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China
关键词:
非顺应性球囊后扩张; 药物洗脱支架; 血栓形成
Keywords:
postdilatation with noncompliance balloon;  drug-eluting stent;  thrombosis
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的: 评价非顺应球囊后扩张对药物洗脱支架（DES）植入后支架内亚急性血栓的影响。方法: 2006年1月~2008年9月住院并植入DES共305例，根据是否采用非顺应球囊后扩张分为非后扩张组及后扩张组，记录所有患者的临床特征、冠脉病变情况、DES植入情况及亚急性血栓形成情况，观察并分析非顺应性球囊后扩张患者发生亚急性血栓形成的情况。结果: 两组患者的临床特征、冠脉病变情况、支架植入数量及平均长度均无统计学差异。非后扩张组及后扩张组支架内亚急性血栓发生率分别为1.2%和0%，没有统计学差异。结论: 非顺应性球囊后扩张不能显著降低DES植入后亚急性血栓发生率。
Abstract:
AIM: To evaluate the influence of postdilatation with noncompliance balloon on subacute thrombosis after implanting intracoronary drug-eluting stents (DES). METHODS: A cohort of 305 consecutive coronary heart disease patients with DES implanted from January 2006 to September 2008 were divided into two groups: postdilatation group and non-postdilatation group. Clinical features, pathological changes of coronary arteries, implantation of drug-eluting stents and formation of subacute thrombosis were recorded and compared. Effects of postdilatation on subacute thrombosis were observed and analyzed. RESULTS: No statistical differences were observed in clinical features, pathological changes of coronary arteries and the number of DES implanted between groups. The rates of subacute thrombosis in the two groups were 1.2% and 0%, respectively, with no significant difference. CONCLUSION: Postdilatation with noncompliance balloon after DES deployment did not significantly reduce the rate of subacute thrombosis.

参考文献/References

［1］Tsimikas S. Drug-eluting stents and late adverse clinical outcomes lessons learned, lessons awaited［J］. J Am Coll Cardiol, 2006, 47(10):2112-2115.

［2］Rodriguez AE, Mieres J, Fernandez-Pereira C, et al. Coronary stent thrombosis in the current drug-eluting stent era: insights from the ERACI III trial［J］. J Am Coll Cardiol, 2006, 47(1):205-207.

［3］ Cheneau E, Leborgne L, Mintz GS, et al. Predictors of subacute stent thrombosis: results of a systematic intravascular ultrasound study［J］. Circulation, 2003, 108(1):43-47.

［4］Fujii K, Carlier SG, Mintz GS, et al. Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation: an intravascular ultrasound study［J］. J Am Coll Cardiol, 2005, 45(7):995-998.

［5］Chieffo A, Stankovic G, Bonizzoni E, et al. Early and mid-term results of drug-eluting stent implantation in unprotected left main ［J］. Circulation, 2005, 111(6):791-795.

［6］Gao Z, Yang YJ, Xu B, et al. Is adjunctive balloon postdilatation necessary with drug-eluting stents? One center experience in Chinese patients［J］. Chin Med J (Engl), 2008, 121(6):513-517.

备注/Memo

备注/Memo:
收稿日期：2009-05-28.作者简介：周圣华，主治医师，博士Email：zhoush516@yahoo.com.cn
更新日期/Last Update: 2010-06-22