我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

半乳糖凝集素-3与心力衰竭的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2011年第5期
页码:
681-683
栏目:
综述
出版日期:
2011-10-25

文章信息/Info

Title:
-
作者:
梁万添徐 新
广东省粤北人民医院心血管内科,广东 粤北 512026
Author(s):
-
关键词:
galectin-3心力衰竭巨噬细胞
Keywords:
-
分类号:
R541.61
DOI:
-
文献标识码:
A
摘要:
研究证实,心力衰竭(HF)的病理生理过程是一个持续的全身性炎症反应。半乳糖凝集素-3(galectin-3)是作为一种炎症因子,参与细胞黏附、增殖、凋亡以及炎症、免疫反应等过程。近来研究发现,galectin-3可通过介导纤维母细胞激活及巨噬细胞浸润,参与HF的病理生理过程,同时可以预测HF患者的预后情况。本文对galectin-3与HF关系的研究进展作一综述。
Abstract:
-

参考文献/References

[1]De Boer RA,Yu L,van Veldhuisen DJ.Galectin-3 in cardiac remodeling and heart failure[J].Curr Heart Fail Rep,2010,7(1):1-8.

[2]Helming L,Gordon S.Macrophage fusion induced by IL-4 alternative activation is a multistage process involving multiple target molecules[J].Eur J Immunol,2007, 37(1):33-42.

[3]Henderson NC,Mackinnon AC,Farnworth SL,et al.Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis[J].Am J Pathol,2008,172(2):288-298.

[4]Henderson NC,Sethi T.The regulation of inflammation by Galectin-3[J].Immunol Rev,2009, 230(1):160-171.

[5]MacKinnon AC,Farnworth SL,Hodkinson PS,et al.Regulation of alternative macrophage activation by Galectin-3[L].J Immunol,2008,180(4):2650-2658.

[6]Parish RC,Evans JD.Inflammation in chronic heart failure[J].Ann Pharmacother,2008,42(7):1002-1061.

[7]Thandavarayan RA,Watanabe K,Ma M,et al.14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy[J].Biochem Pharmacol,2008,75(9):1797-1806.

[8]de Cavanagh EM,Ferder M,Inserra F,et al.Angiotensin II,mitochondria,cytoskeletal,and extracellular matrix connections:an integrating viewpoint[J].Am J Physiol Heart Circ Physiol,2009,296(3):H550-H558.

[9]Sharma U,Rhaleb NE,Pokharel S,et al.Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertensioninduced target organ damage[J].Am J Physiol,2008,294(3):H1226- H1232.

[10]琚长霖,高大胜.血钾在动脉粥样硬化及其相关疾病中的作用[J].心脏杂志,2011,23(1)126-128.

[11]Milting H,Ellinghaus P,Seewald M,et al.Plasma biomarkers of myocardial fibrosis and remodeling in terminal heart failure patients supported by mechanical circulatory support devices[J].J Heart Lung Transplant,2008,27(6):589-596.

[12]Lin YH,Lin LY,Wu YW,et al.The relationship between serum Galectin-3 and serum markers of cardiac extracellular matrix turnover in heart failure patients[J].Clin Chim Acta,2009,409(1-2):96-99.

[13]Shah RV,Chen-Tournoux AA, Picard MH,et al.Galectin-3,cardiac structure and function, and long-term mortality in patients with acutely decompensated heart failure[J].Eur J Heart Fail,2010, 12(8):826-832.

[14]Lok DJ,Van Der Meer P,de la Porte PW,et al.Prognostic value of Galectin-3,a novel marker of fibrosis,in patients with chronic heart failure:data from the DEAL-HF study[J].Clin Res Cardiol,2010,99(5):323-328.

备注/Memo

备注/Memo:
收稿日期:2010-11-08.通讯作者:徐新,主任医师,主要从事冠心病预防研究Email:03xuxin@163.com 作者简介:梁万添,硕士生Email:sthsomelove@163.com
更新日期/Last Update: 2011-11-03