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Title:: Follow-up: correlation between obstructive sleep apnea syndrome and hypertension

作者:: 刘春君¹; 李静¹; 杨月琴¹; 慈书平²; 倪竟全²; 朱爱华²; 罗艳³; (1.解放军322医院门诊部，山西大同037600；
2.解放军第359医院老干部科，江苏镇江 212001；
3.首都医科大学附属北京地坛医院物理诊疗科，北京 100015)

Author(s):: LIU Chun-jun¹; LI Jing¹; YANG Yue-qin¹; CI Shu-ping²; NI Jing-quan²; ZHU Ai-hua²; LUO Yan³; (1.Outpatient Department, PLA 322 Hospital, Datong 037600, Shanxi, China; 2.Department of Elderly Medicine, PLA 359 Hospital, Zhenjiang 212001, Jiangsu, China; 3.Ditan Hospital, Capital Medical University, Beijing 100015, China)

关键词:: 睡眠呼吸暂停综合征; 阻塞性; 高血压病; 流行病学; 随访

Keywords:: sleep apnea syndrome; obstructive; hypertension; epidemiological survey; follow-up

分类号:: R113

DOI:: -

文献标识码:: A

摘要:: 目的:随访阻塞性睡眠呼吸暂停综合征（OSAS）与高血压病的关系。方法：对1 868例人群进行随访，采用家访，随访期间每年进行1次体检，检测血压、血脂、血糖、心电图及X线胸片等，随访时间为20年。结果：随访终点OSAS组（n=598）发生高血压病477例(79.8%)、对照组(n=1 270)发生高血压病323例(25.4%，P<0.01)。结论： OSAS与高血压的发生有关。OSAS是高血压的危险因素。

Abstract:: AIM:To explore the correlation between obstructive sleep apnea syndrome (OSAS) and hypertension. METHODS: Prospective home-visit questionnaires were used in 1868 subjects from November 1989 to November 2009, accompanied by annual medical examinations including blood pressure, blood lipids, serum glucose, electrocardiogram and chest x-ray, and the results were analyzed. RESULTS: Among the 1 868 subjects ［956 males, 912 females aged from (53-82) years with a mean of (63±6) years］, 598 (32.0%) were diagnosed as having OSAS. Hypertension was found in 477 cases (79.8%) in the OSAS group (n=598) and 323 cases (25.4%) in the control group (n=1 270) by the end of the 20-year follow-up. There was significant difference in two groups (P<0.01). CONCLUSION: The probability of hypertension in people with OSAS is higher than in persons without OSAS, indicating a correlation between OSAS and hypertension. OSAS may be an independent harmful factor for development of hypertension.

参考文献/References

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阻塞性睡眠呼吸暂停综合征与高血压病关系的随访研究

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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