我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

低分子肝素和普通肝素在主动脉内球囊反搏术中抗凝应用的临床观察

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2012年第5期
页码:
620-621
栏目:
临床研究
出版日期:
2012-10-25

文章信息/Info

Title:
Study on the clinical effects of low molecular weight heparin and unfractionated heparin in intra-aortic balloon pump surgery
作者:
文亚红; 曾晓斌; 田巨龙; 兰建军; 徐大文; 赵 颖
(攀枝花市中心医院心内科，四川 攀枝花 617067)
Author(s):
WEN Ya-hong;  ZENG Xiao-bin;  TIAN Ju-long;  LAN Jian-jun;  XU da-wen;  ZHAO Ying
(Department of Cardiology, Central Hospital of Panzhihua City, Panzhihua, 617067, Sichuan, China)
关键词:
低分子肝素; 主动脉; 球囊反搏术
Keywords:
low molecular weight heparin;  aorta;  balloon pump surgery
分类号:
R543.1
DOI:
-
文献标识码:
A
摘要:
目的:观察低分子肝素(LMWH) 和普通肝素（UFH）在主动脉内球囊反搏术（IABP）中抗凝应用的临床效果。方法： 68例安置IABP的患者随机分为应用UFH抗凝的常规组（34例）和应用LMWH抗凝的试药组（34例），观察两组患者的出血、血肿、血栓形成等并发症发生情况及费用差别。结果： 两组均只有少部分患者有伤口少量渗血、局部小血肿和伤口周围轻度青紫等表现，无其它并发症出现，两组比较差异无显著性。但试药组的费用比常规组低，两组比较差异有显著性。结论： 在IABP中应用LMWH可以达到应用UFH相同的抗凝、预防血栓形成的效果，同时并发症无增加，而费用减少。
Abstract:
AIM:To observe the clinical effect of low molecular weight heparin (LMWH) compared with unfractionated heparin (UFH) in intra-aortic balloon pump (IABP) surgery. METHODS: Sixty-eight patients with IABP were randomly divided into two groups: conventional group (34 cases) using UFH anticoagulation and observation group (34 cases) using LMWH anticoagulation. The incidence of bleeding, hematoma, thrombosis and other complications, as well as the cost in the two groups, were recorded. RESULTS: Only slight wound bleeding, local small hematoma and mild bruising around the wound were observed in a low percentage of the patients, with no significant difference between groups. However, the cost in the observation group was significantly lower than in the conventional group. CONCLUSION: LMWH has a low cost and is more convenient and if as effective as UFH in regard to anticoagulant and antithrombotic effect for IABP.

参考文献/References

[1]张治云,凌沛学,王凤山,等.低分子肝素药理作用研究进展[J].食品与药品,2006,8(1):7-9.
[2]林 平，林 英，王晓红.低分子肝素[J].临床军医杂志,2006,34(5):630-632.
[3]Arbit E.Low-molecular-weight heparin and outcomes[J].Chest,2005,128(1):471.
[4]White HD,GalIo R,Cohen M,et al. The use of intravenous enoxaparin in elective percutaneous coronary intervention in patients with renalimpairment:results from the safety and efficacy of enoxaparin in PCI patients,an international randomized evaluation(STEEPLE)trial[J].Am Heart J,2009,157(1):125-131.
[5]王泰然，张玉东. 低分子肝素在急性冠脉综合征和冠心病治疗中的应用[J].心脏杂志,2007,19(4):484-487.
[6]纪 辉，金丽娟，李学奇，等.那屈肝素在冠状动脉介入治疗中的效果和安全性[J].心脏杂志,2007,19(1):53-55.

备注/Memo

备注/Memo:
收稿日期：2012-04-04.
作者简介：文亚红，副主任医师Email:pzhwyhyj@163.com
更新日期/Last Update: 2012-11-16