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¡¶ÐÄÔàÔÓÖ¾¡·[ISSN:1009-7236/CN:61-1268/R]

ÆÚÊý:

2012ÄêµÚ6ÆÚ

Ò³Âë:

719-722

À¸Ä¿:

ÁÙ´²Ñо¿

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2012-12-25

ÎÄÕÂÐÅÏ¢/Info

Title:

Risk factor for acute ST-segment elevation myocardial infarction in young adults

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Author(s):

LI Dong-bao¹;  CHEN Wen-ming¹;  HUA Qi²;  LIU Zhi²

(1.Department of Cardiology, Beijing Friendship Hospital, Beijing 100050, China, 2.Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China)

¹Ø¼ü´Ê:

Ðļ¡¹£ËÀ; ¼±ÐÔ; ÄêÇá; Î£ÏÕÒòËØ; Ô¤ºó

Keywords:

acute myocardial infarction;  young adults;  prognosis;  risk factor

·ÖÀàºÅ:

R541.4

DOI:

-

ÎÄÏ×±êʶÂë:

A

ÕªÒª:

Ä¿µÄ:·ÖÎö¼±ÐÔST¶Î̧¸ßÐÍÐļ¡¹£ËÀ(STEMI) »¼ÕßÖÐÄêÇỼÕßµÄÁÙ´²Ìص㡣·½·¨£º Á¬ÐøÈëÑ¡1995Äê4ÔÂ~2005Äê5ÔÂÈëÔºµÄ1 137ÃûSTEMI»¼Õߣ¬¸ù¾ÝÄêÁä·ÖΪ3×飺21~40Ë꣨n=55£©¡¢41~60Ë꣨n=364£©ÒÔ¼°61~90Ë꣨n=718£©£¬ÊÕ¼¯ÆäÐÄѪ¹ÜΣÏÕÒòËØ¡¢ÈË¿Úͳ¼ÆѧÌصãÒÔ¼°Ñª¹ÜÓ°Ïñѧ½á¹û²¢½øÐзÖÎö¡£½á¹û£º Á¬Ðø10ÄêÄÚÈëס±¾ÔºµÄSTEMI»¼ÕßÖ»ÓÐ4.84%µÄ»¼ÕßÄêÁäСÓÚ40Ë꣬ÕâЩ»¼ÕßÄÐÐԾӶ࣬¶à¾ßÓÐÎüÑÌÊ·¡¢Òû¾ÆÊ·£¨P<0.01£©£»ÌÇÄò²¡ºÍ¸ßѪѹ²¡ÔÚÄêÇỼÕßÖÐÏà¶Ô½ÏÉÙ£»ÑªÖ¬·ÖÎöÏÔʾÄêÇỼÕß×ܵ¨¹Ì´¼¡¢µÍÃܶÈÖ¬µ°°×µ¨¹Ì´¼¡¢¸ßÃܶÈÖ¬µ°°×µ¨¹Ì´¼ºÍÈýõ£¸ÊÓÍÖµ¾ùÏà¶Ô½Ï¸ß£¨P<0.01£©£»Ñª¹ÜÔìÓ°½á¹ûʾÄêÇỼÕ߶àΪµ¥Ö§Ñª¹Ü²¡±ä£¨P<0.01£©£»ÔºÄÚ¼°5ÄêÈ«Òò²¡ËÀÂÊÏà¶ÔÄêÀÏ»¼Õß¾ù½ÏµÍ£¨P<0.01£©¡£½áÂÛ£º ÄêÇỼÕß¾ßÓÐÃ÷ÏÔ²»Í¬µÄΣÏÕÒòËØ×é³ÉºÍѪ¹ÜÓ°Ïñѧ½á¹û£¬²»¹ý£¬ÕâЩ»¼Õß¾ßÓÐÏà¶Ô½ÏºÃµÄ¶ÌÆںͳ¤ÆÚÔ¤ºó¡£

Abstract:

AIM:To analyze the risk factors of acute ST-segment elevation myocardial infarction (STEMI) in young adults with acute myocardial infarction (AMI). METHODS: A cohort of 1137 consecutive STEMI patients admitted to our hospitals from April 1995 to May 2005 were divided into three groups according to ages: 21- to 40-year-old group (n=55), 41- to 60-year-old group (n=364) and 61- to 90-year-old group (n=718). Data on clinical cardiovascular risk factors, demographic features and angiographic findings were gathered and analyzed. RESULTS: Only 4.84% of the hospitalized STEMI patients over the 10-year period were <40 years of age. Young adults were found to be predominantly male and most had a smoking and alcohol history (P<0.01). Diabetes and hypertension were less prevalent in the group of young adults. Analysis of lipid profiles showed comparatively higher total cholesterol, low-density lipoprotein, high-density lipoprotein and triglyceride values in the young age group (P<0.01). Angiography showed a high propensity toward single-vessel involvement in the young adult group (P<0.01). In-hospital and 5-year all-cause deaths in the young age group were lower than those in older adults (P<0.01). CONCLUSION: The risk factor profile and angiographic involvement differ considerably between the high-risk young population and older adults. However, the short- and long-term prognosis in young adults is more favorable.

²Î¿¼ÎÄÏ×/References

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