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IIb/IIIa受体抑制剂治疗急性冠脉综合征的最新研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2014年第2期
页码:
233-235238
栏目:
综述
出版日期:
2014-01-20

文章信息/Info

Title:
Latest research progress in IIb/IIIa receptor inhibitor treatment of acute coronary syndrome
作者:
徐 伟12综述曹 蘅1审校
(皖南医学院:1.弋矶山医院心内科,安徽 芜湖 241001,2.心血管内科,安徽 芜湖 241002)
Author(s):
XU Wei12 CAO Heng1
(1.Department of Cardiology, Yijishan Hospital, Wuhu 241001, Anhu, China, 2.Department of Cardiology, Wannan Medical College, Wuhu 241002, Anhui, China)
关键词:
IIb/IIIa受体抑制剂急性冠脉综合征经皮冠状动脉介入术
Keywords:
IIb/IIIa receptor inhibitor percutaneous coronary intervention acute coronary syndrome
分类号:
R543.3
DOI:
-
文献标识码:
A
摘要:
急性冠脉综合征(acute coronary syndrome,ACS)是严重威胁人类健康的一类急性心血管事件,包括不稳定型心绞痛、非S-T段抬高性心肌梗死(non-ST-segment elevation myocardial infarction,NSTEMI)和S-T段抬高性心肌梗死(ST-segment elevation myocardial infarction,STEMI),以及以上各病症导致的猝死。直接经皮冠状动脉介入术(PCI)已显示是一种治疗ACS的有效方法。接受PCI治疗期间,使用糖蛋白IIb/IIIa受体抑制剂可以减少ACS患者血栓并发症的发生。
Abstract:
Acute coronary syndrome (ACS) is a serious acute cardiovascular event threatening human health, including unstable angina, non-ST-segment elevation myocardial infarction, ST-segment elevation myocardial infarction, and sudden death caused by the above-mentioned cardiac problems. Direct percutaneous coronary intervention (PCI) has been proved an effective method of treatment for ACS. During PCI therapy, the use of glycoprotein IIb/IIIa receptor antagonists can reduce thrombosis complications in ACS patients.

参考文献/References

[1]郑 艳.盐酸替罗非班在急性冠脉综合征治疗中的应用[J].中国现代药物应用,2011,12(5):55-56.
[2]Angiolillo DJ.The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day[J].Drugs,2012,72(16):2087-2116.
[3]Armstrong PC,Peter K.GPIIb/IIIa inhibitors:from bench to bedside and back to bench again[J].Thromb Haemost, 2012,107(5):808-814.
[4]Starnes HB,Patel AA,Stouffer GA.Optimal use of platelet glycoprotein IIb/IIIa receptor antagonists in patients undergoing percutaneous coronary interventions[J].Drugs,2011,71(15):2009-2030.
[5]Panduranga P,Sulaiman K.Severe thrombocytopenia following tirofiban infusion[J].Indian Pharmacol,2011,43(6):726-728.
[6]Elcioglu OC,Ozkok A,Akpnar TS,et al.Severe thrombocytopenia and alveolar hemorrhage represent two types of bleeding tendency during tirofiban treatment: case report and literature review[J].Int J Hematol,2012,96(3):370-375.
[7]马东星,刘惠亮,姚宏英,等.急诊经皮冠状动脉介入治疗术中冠状动脉内注射盐酸替罗非班对急性ST段抬高型心肌梗死患者心肌灌注及心功能的影响[J].中国全科医学, 2010,13(2):476.
[8]Balghith MA.High bolus tirofiban vs abciximab in acute STEMI patients undergoing primary PCI-the tamip study[J].Heart Views,2012,13(3):85-90.
[9]高振华,袁如玉,李广平.替罗非班在老年急性心肌梗死临床应用的有效性及安全性研究[J].中国全科医学,2011,14(7):2385-2387.
[10]穆金兴.盐酸替罗非班在急性心肌梗死急诊冠脉介入治疗中的应用[J].中国误诊学杂志,2010,10(13):3049.
[11]Kubica A,Kozinski M,Navarese EP,et al.Intracoronary versus intravenous abciximab administration in STEMI patients: overview of current status and open questions[J].Curr Med Res Opin,2011,27(11):2133-2144.
[12]Desch S,Siegemund A,Scholz U,et al.Platelet inhibition and GP IIb/IIIa receptor occupancy by intracoronary versus intravenous bolus administration of abciximab in patients with ST-elevation myocardial infarction[J].Clin Res Cardiol, 2012,101(2):117-124.
[13]Shimada YJ,Nakra NC,Fox JT,et al.Meta-analysis of prospective randomized controlled trials comparing intracoronary versus intravenous abciximab in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention[J].Am Cardiol,2012,109(5):624-628.
[14]Wang Y,Wu B,Shu X.Meta-analysis of randomized controlled trials comparing intracoronary and intravenous administration of glycoprotein IIb/IIIa inhibitors in patients with ST-elevation myocardial infarction[J].Am Cardiol,2012,109(8):1124-1130.
[15]Thiele H,W?hrle J,Neuhaus P,et al.Intracoronary compared with intravenous bolus abciximab application during primary percutaneous coronary intervention: design and rationale of the Abciximab Intracoronary versus intravenously Drug Application in ST-Elevation Myocardial Infarction(AIDA STEMI)trial[J].Am Heart J,2010,159(4):547-554.
[16]Sardella G,Sangiorgi GM,Mancone M,et al.A multicenter randomized study to evaluate intracoronary abciximab with the clearway catheter to im-prove outcomes with lysis (IC ClearLy):trial study design and ratio-nale[J].Cardiovasc Med, 2010, 11(7):529-535.
[17]Gibson CM,Maehara A,Lansky AJ,et al.Rationale and design of the INFUSE-AMI study:a 2×2 factorial, randomized, multicenter, single-blind evaluation of intra-coronary abciximab infusion and aspiration thrombectomy in patients undergoing percutaneous coronary intervention for anterior ST-seg-ment elevation myocardial infarction[J].Am Heart,2011,161(3):478-486.
[18]De Vita M,Coluccia V,Burzotta F,et al.Intracoronary use of GP IIb/IIIa inhibitors in percutaneous coronary interventions[J].Curr Vasc Pharmacol,2012,10(4):448-453.
[19]Jing BB,Li YX,Zhang H,et al.Antithrombotic effect of Z4A5 on coronary thrombosis in a canine model of acute unstable angina[J].Br Pharmacol,2013,169(4):848-859.

备注/Memo

备注/Memo:
收稿日期:2013-11-15.
通讯作者:曹蘅,主任医师,主要从事心血管病研究Email:yjscaoheng@163.com
作者简介:徐伟,硕士生Email:295439625@qq.com
更新日期/Last Update: 2014-01-16