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|本期目录/Table of Contents|

急性心肌梗死恢复期新发房颤的发生率与危险因素

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第5期
页码:
585-587
栏目:
临床研究
出版日期:
2015-05-05

文章信息/Info

Title:
Risk factors of new-onset atrial fibrillation during recovery period of acute myocardial infarction
作者:
汪沁沁1叶晨阳2任雨笙1樊 民1吴宗贵1
(1.第二军医大学长征医院心血管内科,上海 200003;
2.北京307医院消化肿瘤科,北京 100071)
Author(s):
WANG Qin-qin1 YE Chen-yang2 REN Yu-sheng1 FAN Min1 WU Zong-gui1
(1.Department of Cardiology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;
2.Department of Digestive Tumors, PLA 307 Hospital, Beijing 100071, China)
关键词:
心肌梗死急性房颤 危险因素logistic回归模型
Keywords:
acute myocardial infarction atrial fibrillation risk factors logistic regression models
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 分析急性心肌梗死(AMI)患者恢复期(心肌梗死28 d后)出现新发房颤的发生率与危险因素。方法 回顾性分析2009年6月~2011年6月全部212例因AMI入住长征医院治疗且无房颤病史的患者一般情况,相关检查结果,以及心肌梗死1年内后续治疗、转归情况,并对可能影响患者恢复期新发房颤的因素进行logistic回归模型分析。结果 多因素logistic回归分析表明,高龄(P<0.05,OR=5.61),高血压病(P<0.05,OR=5.89),左心室射血分数(LVEF)降低(P<0.01,OR=6.3),未行急诊经皮冠状动脉介入(PCI)术(P<0.01,OR=6.01),糖尿病(P<0.05,OR=3.59)以及出院后无法耐受β受体阻滞剂治疗(P<0.01,OR=6.1)等是新发房颤的危险因素。结论 AMI患者恢复期出现新发房颤的危险因素为高龄,高血压病,LVEF降低,未行急诊PCI术,糖尿病以及出院后无法耐受β受体阻滞剂治疗。
Abstract:
AIM To explore the risk factors of new onset atrial fibrillation (AF) during the recovery period (>28 days) of acute myocardial infarction (AMI). METHODS Clinical data of 212 AMI patients during 1 year after admission were retrospectively analyzed, including the general conditions, test results, treatment and follow-up data. Patients were admitted to hospital for AMI from June 2009 to June 2011. Logistic regression analysis was conducted to analyze the risk factors of new-onset AF after hospital discharge. RESULTS Logistic regression analysis showed that age >75 years (P<0.05, OR=5.61), hypertension (P<0.05, OR=5.89), LVEF<50% (P<0.01, OR=6.3), non-emergency PCI (P<0.01, OR=6.01), diabetes mellitus (P<0.05, OR=3.59) and β-blocker intolerance (P<0.01, OR=6.1) were associated with an increased risk of new-onset AF during the recovery period of myocardial infarction. CONCLUSION Age >75 years, hypertension, LVEF<50%, non-emergency PCI, diabetes mellitus and β-blocker intolerance are risk factors for new-onset AF during the recovery period of AMI.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期:2015-01-25.
通讯作者:吴宗贵,主任医师,主要从事冠心病治疗和预防研究 Email:zgwu@medmail.com.cn
共同通讯作者:任雨笙,主任医师,主要从事冠心病基础和临床研究 Email:renyusheng@gmail.com
作者简介:汪沁沁,主治医师,硕士 Email:wqq830824@163.com
更新日期/Last Update: 2015-04-28