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|本期目录/Table of Contents|

抑郁与冠状动脉病变特点的相关性

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2016年第3期
页码:
305-308
栏目:
临床研究
出版日期:
2016-01-05

文章信息/Info

Title:
Correlation between depression and coronary artery lesion
作者:
朱 涛; 孙晓斐; 徐勤成; 魏子秀; 田飞飞; 冯传明
（济南大学、山东省医学科学院 济宁市第一人民医院心内科，山东 济宁 272013）
Author(s):
ZHU Tao;  SUN Xiao-fei;  XU Qin-cheng;  WEI Zi-xiu;  TIAN Fei-fei;  FENG Chuan-ming
(Department of Cardiology, Jining First People’s Hospital, University of Jinan & Academy of Medical Sciences, Jining 272013, Shandong, China)
关键词:
抑郁; 冠脉病变特点; 冠脉病变支数; 冠脉狭窄程度; 相关性
Keywords:
depression;  lesion characteristics;  number of lesions;  severity of coronary stenosis;  correlation analysis
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 分析抑郁与冠心病患者冠状动脉病变支数及冠状动脉狭窄程度的相关性。方法 随机选取我院2014年1月~2015年1月初步诊断为冠心病的患者353例，均行汉密尔顿抑郁量表（HAMD）测评，根据测评结果分为抑郁组及非抑郁组，然后行冠状动脉造影检查，分析比较两组患者冠脉病变支数及冠脉狭窄程度。结果 两组患者在冠状动脉病变支数和冠状动脉狭窄程度分布构成比上均存在显著差异（均P<0.01)；抑郁组患者3支病变及冠脉狭窄c级和d级所占的比例更高，分别为37.0%、36.1%和38.0%，与非抑郁组患者相比，具有显著性差异（均P<0.05）；非抑郁组患者其单支病变、狭窄a级和狭窄b级比例比较，分别为44.6%、31.0%、31.4%，与75岁及以上患者比有统计学差异（均P<0.05）。结论 抑郁患者的冠状动脉病变累及支数较多且狭窄程度较重。
Abstract:
AIM To examine the correlation between depression and the number of coronary artery lesions and the severity of coronary stenosis in patients with coronary heart disease (CHD). METHODSThree hundred and fifty-three hospitalized patients with preliminary diagnosis of CHD from January 2014 to January 2015 in our hospital were randomly selected and divided into depression group and non-depression group after Hamilton depression rating scale measurement. Coronary angiography examination was performed in all patients and the number of coronary artery lesions and severity of coronary stenosis were compared between groups. RESULTSThe distribution constituent ratio of the lesion vessel number and the coronary artery stenosis degree was significantly different between groups (both P<0.01). The proportion of grade C and grade D and triple vessel lesions in depression group was significantly higher (36.1%, 38.0% and 37.0%) than those in non-depression group (all P<0.05). The proportion of single vessel lesion and grade A and grade B in non-depression group was significantly higher (44.6%, 31.0% and 31.4%) than those in depression group (all P<0.05). CONCLUSIONThe number of coronary artery lesions is higher and coronary stenosis is more severe in CHD patients with depression.

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备注/Memo

备注/Memo:
收稿日期：2015-07-29.
通讯作者：孙晓斐，主任医师，主要从事冠心病和心脏电生理与起搏研究 Email:xgcheng555@sina.com
作者简介：朱涛，硕士生 Email：578057603@qq.com
更新日期/Last Update: 2016-01-07