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高血压病患者并发中心性肥胖的相关因素及其腹围与动态血压相关性(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第3期
页码:
317-321
栏目:
临床研究
出版日期:
2017-01-25

文章信息/Info

Title:
Association between abdominal girth and ambulatory blood pressure in patients with central obesity combined with hypertension
作者:
万 进1; 王光耀2; 何安霞1
南京中医药大学：1.附属江苏省中医院心内科,江苏 南京 210029，2.基础医学院中基内经教研室，江苏 南京 210023
Author(s):
WAN Jin1;  WANG Guang-yao2;  HE An-xia1
1.Department of Cardiology, Affiliated Hospital, Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu, China; 2.In the Media Department, College of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu, China
关键词:
动态血压; 高血压; 原发性; 中心型肥胖; 腹围
Keywords:
ambulatory blood pressure;  hypertension;  central obesity;  abdominal girth
分类号:
R540.41
DOI:
-
文献标识码:
A
摘要:
目的 分析高血压病患者并发中心性肥胖的相关因素及其腹围和动态血压（ABPM）的相关性。方法 回顾性分析100例中心性肥胖并发高血压病患者（病例组）的资料，分为男性组（n=50）、女性组（n=50）。另设无中心性肥胖的高血压病患者作为对照组（n=100）。比较腹围和ABPM的关系。腹围和血压的相关性研究采用直线相关分析，并采取控制影响因素的偏相关分析。结果 男性组和女性组年龄匹配。二组24h收缩压(SBP)均值、白天SBP均值、夜晚SBP均值最高SBP均值均增高。二组比较差异无统计学意义。腹围与24SBP均值、白天SBP均值、夜晚SBP均值、最高SBP均值呈正相关（男性r=0.282、r=0.360、r=0.238、r=0.380，均P<0.05；女性r=0.350、r=0.342、r=0.335、r=0.344，均P<0.05）。腹围与昼夜节律呈负相关，男性r=-0.278/-0.058；女性r=-0.264/-0.027，均P<0.05/P>0.05。腹围与24hSBP负荷均值呈正相关（男性r=0.339、女性r=0.321，P<0.05）。结论 中心性肥胖并发高血压病患者腹围与收缩压、收缩压负荷、昼夜节律相关。
Abstract:
AIM To study the relation between abdominal girth and ambulatory blood pressure monitoring (ABPM) in patients with central obesity combined with hypertension. METHODS A retrospective study of 100 cases of central obesity combined with hypertension was conducted with 50 males and 50 females. The control group consisted of 100 hypertensive patents with no central obesity. The association between abdominal girth and ABPM was studied with a linear correlation and with partial correlation to control the influencing factors. RESULTS Males and females were age matched. Average 24-h systolic blood pressure (SBP) and average diurnal and nocturnal SBP all increased in both groups, but without statistical significance between groups (t=0.869, t=1.347, t=0.340, t=0.140, P>0.05). Abdominal girth was positively associated with average 24-h SBP, average diurnal and nocturnal SBP and average SBP max (male: r=0.282, r=0.360, r=0.238, r=0.380, P<0.05; female: r=0.350, r=0.342, r=0.335, r=0.344, P<0.05). Abdominal girth was negatively associated with circadian rhythms (male r=-0.278/-0.058; female r=-0.264/-0.027, all P<0.05/P>0.05) but was positively associated with average 24-h SBP load (male r=0.339, female r=0.321, P<0.05). CONCLUSION Abdominal girth of patients with central obesity combined with hypertension is associated with SBP, SBP load and circadian rhythms, indicating abdominal girth should be controlled.

参考文献/References

[1]Calhoun DA,J ones D,Text or S,et al.Resistant hypertens ion:diagnosis, evaluation, and treatment.A scientific statement from the Amer can Heart Associat ion Professional Education Committee of t he Council for High Blood Pressure Research[J].Hypertension,2008,51(6):1403-1419.
[2]Straznicky N,Grassi G,Esler M,et al.Eur opean Society of Hypertension Working G oup on Obesity Antihypertensive effects of weight loss:myth or eality[J].J Hypertens,2010,28(4):637-643.
[3]周 敏，何 青.吸烟与冠心病[J].中华心血管病杂志,2010,38(8):763-765.
[4]Zlegler MC.Sleepdisorders and the fallure to lower nocturnal bloodpressure[J].Curs Opln Nephrol Hypertension,2003,12(7):97-102.
[5]Kannel WB.Elevated systolic blood pressure as a cardiovascular risk factor[J].Am J Cardiol,2000,85(2):251-255.
[6]Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP).SHEP Cooperative Research Group[J].JAMA,1991,265(24):3225-3264.
[7]Fang XH,Longstreth WT Jr,Li SC,et al.longitudinal study of blood pressure and stroke in over 37,000 people in china[J].Cerebrovasc Dis,2001,11(3):225-229.
[8]王 薇,赵 冬,刘 军.收缩压及舒张压与脑卒中和冠心病关系的前瞻性研究[J].高血压杂志,2000,8(4):276-277.
[9]Clement DL,De Buyzere ML,De Bacquer DA,et al.Prognostic value of ambulatory blood-pressure recordings in patients with treat-ed hypertension[J].N Engl J Med,2003,348(24):2407-2415.
[10]Metoki H,Ohkubo T,Kikuya M,et al.Prognostic significance for stroke of a morning pressor surge and a nocturnal blood pressure de-cline:the Ohasama study[J].Hypertension,2006,47(2):149-154.
[11]Holt-Lunstad J,Steffen PR.Diurnal cortisol variation is associated with nocturnal blood pressure dipping[J].Psychosom Med,2007,69(4):339-343.
[12]Hermida RC,Ayala DE,Portaluppi F.Circadian variation of bloodpressure: The basis for the chronotherapy of hypertension[J].Ad-vanced Drug Delivery Reviews,2007,59(9-10):904-922.
[13]De la Sierra A,Redon J,Banegas JR,et al.Prevalence and factors associated with circadian blood pressure patterns in hypertensive pa-bents[J].Hypertension,2009,53(3):466-472.
[14]Ceriello A,Davidson J,Hanefeld M,et al.Postprandial hyperglycaemia and cardiovascular complications of diabetes: An update[J].Nutr Metab Cardiovasc Dis,2006,16(7):453-456.
[15]Ghosh A,Bose K,Chakravarti S,et al.Central obesity and coronary risk factors[J].J R Soc Promot Health,2004,124(3):86-90.

备注/Memo

备注/Memo:
收稿日期：2016-05-16.作者简介：万进，主任医师，硕士 Email:nanjingdoctor@163.com
更新日期/Last Update: 2017-02-20