我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

不同血压水平与冠脉病变及临床事件的相关性(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2017年第3期
页码:
325-328
栏目:
临床研究
出版日期:
2017-01-25

文章信息/Info

Title:
Relationship between hypertension classifications and clinical events in patients with coronary artery lesions
作者:
王宗方; 柏 战
芜湖市第二人民医院心内科，安徽 芜湖 241000
Author(s):
WANG Zong-fang;  BAI Zhan
Department of Cardiology, Second People’s Hospital of Wuhu, Wuhu 241000, Anhui, China
关键词:
冠状动脉硬化; 高血压; 原发性; 冠状动脉造影
Keywords:
coronary arteriosclerosis;  hypertension;  coronary angiography
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的 研究不同血压水平与冠脉病变及临床事件之间的关系。方法 收集我科行冠脉造影患者276例。根据患者血压状况分为血压正常组(82例)，高血压Ⅰ级组(58例)，高血压Ⅱ级组(65例)，高血压Ⅲ级组(71例)。收集临床资料，冠脉评分采用改良的Gensini评分，分析各组冠状动脉造影结果及心脑血管事件发生率。结果 各组冠脉病变程度构成比不同，血压正常组重度病变比例最低，高血压Ⅲ级组重度病变比例最高（P<0.05）；多元逐步回归分析显示，年龄、吸烟、糖尿病、高血压均为Gensini评分的危险因素， 高密度脂蛋白胆固醇为保护因素；随着血压的升高心脑血管事件发生率明显增高（P<0.05）。结论 随着血压的升高，冠脉病变程度加重，心脑血管事件发生率增加。
Abstract:
AIM To investigate the relationship between hypertension classifications and clinical events in patients with coronary artery lesions. METHODS Data of 276 patients undergoing coronary angiography were collected. On the basis of blood pressure levels, patients were divided into normal blood pressure group (n=82), essential hypertension (EH) I group (n=58), EH II group (n=65) and EH III group (n=71). Gensini score was used for coronary assessment. Results of coronary angiography and incidence of clinical events were analyzed in each group and compared between groups. RESULTS The constituent ratio of coronary artery lesion degree was different in each group. The ratio of severe coronary artery lesion in normal blood pressure group was the lowest, whereas that of the EH III group was the highest (P<0.05). Multiple regression analysis showed that age, smoking, diabetes and high blood pressure were risk factors of Gensini score, and HDL-C was a protective factor. With the increase in blood pressure, rate of clinical events markedly increased (P<0.05). CONCLUSION Increasing blood pressure worsens coronary artery lesions and increases the clinical event rate.

参考文献/References

[1]Maroszyńska-Dmoch EM,Wo?akowska-Kap?on B.Clinical and angiographic characteristics of coronary artery disease in young adults:a single centre study[J].Kardiol Pol,2016,74(4):314-321.
[2]Reardon MF,Nestel PJ,Craig IH,et al.Lipoprotein predictors of the severity of coronary artery disease in men and women[J].Circulation,1985,71(5):881-888.
[3]Sullivan DR,Marwick TH,Freedman SM,et al.A new method of scoring coronary angiograms to reflect extent of coronary atherosclerosis and improve correlation with major risk factors[J].Am Heart J,1990,119(6):1262-1267.
[4]Blankstein R,Budoff MJ,Shaw LJ,et al.Predictors of coronary heart disease events among asymptomatic persons with low low-density lipoprotein cholesterol MESA(Multi-Ethnic Study of Atherosclerosis)[J].J Am Coll Cardiol,2011,58(4):364-374.
[5]Christiansen MK,Jensen JM,Br?ndberg AK,et al.Cardiovascular risk factor control is insufficient in young patients with coronary artery disease[J].Vasc Health Risk Manag,2016,25(12):219-227.
[6]Li Z,Cheng J,Wang L,et al.Analysis of high risk factors and characteristics of coronary artery in premenopausal women with coronary artery disease[J]Int J Clin Exp Med,2015,8(9):16488-16495.
[7]Mohammad AM,Jehangeer HI,Shaikhow SK.Prevalence and risk factors of premature coronary artery disease in patients undergoing coronary angiography in Kurdistan,Iraq[J].BMC Cardiovasc Disord,2015,15(1):155.
[8]Zidi W,Allal-Elasmi M,Zayani Y,et al.Metabolic Syndrome,Syndrome, Independent Predictor for Coronary Artery Disease[J].Clin Lab,2015,61(10):1545-1552.
[9]刘 莹，陈庆伟，吴 庆，等.老年人增龄、性别差异与冠心病的相关性研究[J].重庆医科大学学报,2010,35(3):403-407.
[10]Urbieta Caceres VH,Lin J,Zhu XY,et al.Early experimental hypertension preserves the myocardial microvasculature but aggravates cardiac injury distal to chronic coronary artery obstruction [J].Am J Physiol Heart Circ Physiol,2011,300(2):H693-H701.
[11]Chishti T,Harris T,Conroy R,et al.How reliable are stroke patients,reports of their numbers of general practice consultations over 12 months?[J].Fam Pract,2013,30(1):119-122.
[12]Irvin MR,Booth JN,Shimbo D,et al.Apparent treatment-resistant hypertension and risk for stroke, coronary heart disease, and all-cause mortality[J].J Am Soc Hypertens,2014,8(6):119-122.
[13]Teramukai S,Okuda Y,Miyazaki S,et al.Dynamic prediction model and risk assessment chart for cardiovascular disease based on on-treatment blood pressure and baseline risk factors[J].Hypertens Res,2016,39(2):113-118.
[14]Misawa K,Nitta Y,Matsubara T,et al.Difference in coronary blood flow dynamics between patients with hypertension and those with hypertrophic cardiomyopathy[J].Hypertens Res,2002,25(5):711-716.
[15]Paixao AR,Enriquez JR,Wang TY,et al.Risk factor burden and control at the time of admission in patients with acute myocardial infarction:Resultsfrom the NCDR[J].Am Heart,2015,170(1):173-179.
[16]Kotseva K,Wood D,De Bacquer D,et al.EUROASPIRE IV:A European Society of Cardiology survey on the lifestyle,risk factor and therapeuticmanagement of coronary patients from 24 European countries[J].Eur J Prev Cardiol,2016,23(6):636-648.

备注/Memo

备注/Memo:
收稿日期：2016-07-06.作者简介：王宗方，主治医师，硕士 Email：43976403@qq.com
更新日期/Last Update: 2017-02-20