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|本期目录/Table of Contents|

心外膜脂肪对冠心病的影响及干预进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2018年第3期
页码:
340-343,354
栏目:
综述
出版日期:
2018-03-25

文章信息/Info

Title:
Recent advances in effect of epicardial adipose tissue on coronary atherosclerosis disease and its intervention
作者:
单冬凯; 刘昱圻; 陈韵岱
（中国人民解放军总医院心血管内科，北京 100853）
Author(s):
SHAN Dong-kai;  LIU Yu-qi;  CHEN Yun-dai
(Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China)
关键词:
心外膜脂肪组织; 冠状动脉粥样硬化性心脏病; 脂肪因子; 冠状动脉狭窄
Keywords:
epicardial adipose tissue;  coronary atherosclerosis disease;  adipokines;  coronary artery stenosis
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
心外膜脂肪组织（EAT）是围绕在心脏和冠状动脉周围的特殊内脏脂肪组织。近年来研究发现，EAT是内源性脂肪和促炎因子的重要来源，可调节冠状动脉粥样硬化性心脏病的发生和发展过程。本文回顾了EAT与冠状动脉粥样硬化性心脏病相关的最新研究进展，并对以EAT为干预靶点，发挥治疗冠心病潜能的相关研究进行综述。
Abstract:
Epicardial adipose tissue, a special visceral adipose tissue surrounding the heart and coronary arteries, recently has been found to be an important source of endogenous adipokines and proinflammatory cytokines. It may be involved in the presence and pathophysiological progress of coronary atherosclerosis disease. This review briefly summarizes recent advances in the relationship between epicardial adipose tissue and coronary atherosclerosis disease and reviews the potentials of epicardial adipose tissue serving as a target for intervention of atherosclerosis.

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备注/Memo

备注/Memo:
收稿日期：2017-03-02.基金项目：国家重点研发计划项目资助（2016YFC1300300） 通讯作者：陈韵岱，教授，主要从事冠心病介入治疗的基础与临床研究 Email:cyundai@vip.163.com 作者简介：单冬凯，博士生 Email:shandongkai1234@163.com
更新日期/Last Update: 1900-01-01