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|本期目录/Table of Contents|

ω-3多不饱和脂肪酸对心血管的保护作用及其分子机制研究

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2018年第5期
页码:
580-583,617
栏目:
综述
出版日期:
2018-06-25

文章信息/Info

Title:
Protective effect and molecular mechanism of omega-3 fatty acids on cardiovascular system
作者:
邱 雅1曹 丰2
(解放军总医院:1.老年医学研究所,2.心内科,北京100853)
Author(s):
QIU Ya1 CAO Feng2
(1.Institute of Geriatrics, 2.Department of Cardiology, PLA General Hospital, Beijing 100853, China)
关键词:
ω-3多不饱和脂肪酸心血管系统二十碳五烯酸二十二碳六烯酸分子机制
Keywords:
omega-3 PUFAs cardiovascular system eicosapentenoic acid docosahexenoic acid molecular mechanisms
分类号:
R322.1
DOI:
-
文献标识码:
A
摘要:
ω-3多不饱和脂肪酸(ω-3 PUFAs)是人体所需的必须脂肪酸,大量证据表明其对心血管具有保护作用,然而机制尚不明确。二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)是鱼油来源的ω-3 PUFAs,可有效防治心血管疾病,相关研究报道较多。本文主要对ω-3 PUFAs的基本特征和对心血管系统的保护作用及其机制研究做一综述。
Abstract:
Omega-3 fatty acids (omega-3 PUFAs) are essential fatty acids in human tissues. Substantial research suggests that Omega-3 exerts a protective effect on cardiovascular system. However, the molecular mechanism is still unclear. Eicosapentenoic acid (EPA) and docosahexenoic acid (DHA) are two kinds of omega-3 PUFAs from fish oils, which have been cited for prevention and treatment of cardiovascular diseases. This paper reviews the basic characteristics of omega-3 PUFAs and their molecular mechanisms of mediating or modulating protective effects on the cardiovascular system.

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备注/Memo

备注/Memo:
收稿日期:2017-08-04.基金项目:国家杰出青年科学基金项目资助(81325009);解放军总医院科技创新苗圃基金项目资助(14KMM20) 通讯作者:曹丰,主任医师,主要从事冠心病基础与临床转化研究 Email:fengcao8828@163.com 作者简介:邱雅,博士生 Email:qiuya720@sina.com
更新日期/Last Update: 1900-01-01