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老年人糖耐量低减的冠心病与B细胞功能及脂代谢的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第6期
页码:
448-449，452
栏目:
论著
出版日期:
2001-11-01

文章信息/Info

Title:
Association between the aged impaired glucose tolerance united coronary heart disease, and Bcell function and lipometabolism
作者:
季洪赞1;  龚维忠3;  杨继红1;  李　琳1;  胡兰萍2;  胡拥军1;  商　玮1
南京军区南京总医院: 1. 老年二科, 2. 内科实验室, 江苏南京210002; 3. 解放军政治学院门诊部
Author(s):
JI Hong-zan1;  GONG Wei-zhong3;  YANG Ji-hong1;  LI Ning1;  HU Lan-ping2;  HU Yong-jun1; SHANG Wei11
1. Second Departemtn of Gerontology, 2. Department of Internal Medicine Laboratory, Army General Hospital of Nanjing,Nanjing Jiangsu 210002, China; 3. College of Politics PLA
关键词:
老年人;  糖耐量低减;  冠状动脉疾病;  B细胞功能;  脂代谢
Keywords:
aged;  impaired glucose tolerance;  coronary disease;  Bcell function;  lipometabolism
分类号:
R541. 4
DOI:
-
文献标识码:
A
摘要:
目的 探讨老年人糖耐量低减(IGT) 的冠心病(CHD) 与B细胞功能及脂代谢的关系。方法 将79 例糖耐量低减老年人分为冠心病组(n= 31) 和非冠心病组(n= 48) ; 糖耐量正常(NGT) 老年人49 例作为对照组。测定空腹胰岛素/空腹血糖(FINS/ FBG)、胰岛素敏感指标( ISI) 及血脂(TC, TG, HDL-C, TC/HDL-C) 并对结果进行分析比较。结果 IGT 冠心病组较之IGT 非冠心病组和NGT 组, 在FINS/ FBG, ISI 差异有显著性(P < 0. 05; P < 0. 01) , TC,TG, TC/HDL-C 的差异亦有显著性(P < 0. 05, P < 0. 05, P < 0. 01) , 老年人IGT 组(n= 79) FINS/ FBG, ISI 较之老年人NGT 组显著减低(P < 0. 01) , 脂代谢紊乱表现为高TC/HDL-C (P < 0. 01) 比值。结论 老年人IGT 应尽早实施保护B细胞功能、降血脂等干预措施。
Abstract:
AIM To study the association between the aged impaired glucose tolerance united coronary heart disease and Bcell function, lipometabolism. METHODS 79 case coronary heart disease of the senile IGT patients and 49 NGT of the senile were examined for B cell function and lipometabolism. The subjects were divided into three groups: CHD groups (n = 31) , not-CHD groups (n= 48) and NGT group (n= 49) . RESULTS The Bcell function (FINS/ FBG, ISI) and lipometabolism (TC/HDL-C) in the IGT group (n= 79) were marked different from those in the controls (NGT ) (P < 0. 05, P < 0. 01). The Bcell function and lipometabolism of the senile IGT patients (n = 79) were much lower than those in the controls (P < 0. 01). CONCLUSION The aged impaired glucose tolerance patients should be protected from damages of Bcell function and intervention of hyperlip idemia should be undertaken as early as possible.

参考文献/References

[1] Pan XR, Li GW , Hu YH, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose to lerance[J]. Diabetes Care, 1997, 20: 537- 544.

[2] Antonucci T,Whitcomb R,Mclian R, et al. Impaired glucose tolerance is normalized by treatment with the thiazo lidinedione troglitazone[J]. Diabetes Care, 1997, 20: 188- 193.

[3] 李光伟, 潘孝仁. 空腹血胰岛素、葡萄糖比值作为B细胞功能指数的可能性[J]. 中华内分泌代谢杂志, 1998, 8: 232.

[4] 李光伟, 潘孝仁,Lillioja S, 等. 检测人群胰岛素敏感性的一项新指数[J]. 中华内科杂志, 1993, 33: 656.

[5] Stenven A G, Cynthia SP, Louis C. Serum lipid screening to identify high-risk individuals for coronary death: The results of the lipid research clinics prevalence cohort [J]. Arch Intern Med , 1994, 154: 679.

[6] Capes SE, Hunt D,Malmberg K, et al. Stress hyperglycemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview [J].Lancet, 2000, 355: 773- 778.

[7] Haffner SM. Impaired glucose tolerance, insulin resistance and cardiovascular disease [J]. Diabetic Med , 1997, 14 ( supp l 3) :s12.

[8] Stenven A G, Louis C, Hu XP. Identifying adults at increased risk of coronary disease[J]. JAMA , 1995, 274: 801.

[9] Illingworth DR. Coronary heart disease of new lyetiological factor[J]. Am J Med , 1999, 107 (2A ) : 195- 215.

备注/Memo

备注/Memo:
收稿日期：2001-01-19.
更新日期/Last Update: 2001-11-01