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|本期目录/Table of Contents|

C反应蛋白与冠心病病变程度相关的研究(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第1期
页码:
25-26
栏目:
论著
出版日期:
2002-01-01

文章信息/Info

Title:
Study of the relation ship between C-reactive protein and severity coronary heart disease
作者:
张利华;  赵季红;  薛玉生;  刘　峰
第四军医大学唐都医院心内科, 陕西 西安 710038
Author(s):
ZHANG Li-hua;  ZHAO Ji-hong ;  XUE Yu-sheng ;  LIU Feng
Department of cardiology, Tangdu Hospital, Fourth Military Medical University, Xian Shaanxi 710038, China
关键词:
冠状动脉疾病;  C 反应蛋白;  冠脉病变支数
Keywords:
C-reactive protein;  coronary disease;  number of diseased coronary vessels
分类号:
R541.4　
DOI:
-
文献标识码:
A
摘要:
目的 探讨血浆C反应蛋白(CRP) 与冠心病(CHD) 病变程度之间的关系。方法 测定经选择性冠状动脉造影(CAG) 证实为CHD患者(n=86) 的血浆CRP 浓度, 并与CAG结果正常组(n=80)的血浆CRP浓度相比较, 分析两组之间以及CHD 组中, 冠状动脉(冠脉) 病变支数与相应CRP 浓度的关系。结果 CRP浓度在对照组、稳定型心绞痛组、不稳定型心绞痛组依次增高, 分别为2293±198, 5126±508 和12969±1076 μg/L 。在CHD 组中, 单支病变组、双支病变组以及三支病变组, 其CRP 浓度也依次增高, 分别为5131±513, 7024±689, 11970±2075 μg/L 。结论 CRP 浓度与冠脉病变程度关联密切。
Abstract:
AIM To explore the relation ship between C-reactive protein (CRP) and the severity of coronary heart disease (CHD). METHODS The plasma CRP concent rations were tested in 166 cases who underwent coronary angiography (CAG) (CHD was present in 86 patients and absent in 80 cases as normal control group ) , and results of the two groups and different numbers of diseased coronary vessels in CHD group were analyzed. RESULTS The plasma CRP concent rations were 2293±198, 5126±508, 12969±1076 Lg/L , respectively, for the normal control group and the stable angina group , the unstable angina group. The indices in the stable angina group and the unstable angina group were significantly higher than those of the normal control group ( P < 0. 05, P < 0. 01 respectively). In the CHD group , the plasma concent rations were, 5131±513, 7024±689, 11970±2075 Lg/L , respectively, for the 1-vessel-disease group ,the 2-vessel-disease group and the 3-vessel-disease group. The indices of the three groups were significantly higher than those of the normal control group (P < 0. 01). CONCLUSION CRP concent ration was closely associated with CHD

参考文献/References

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[2] Yamashito K, Ouchi K, Shirai M , et al. Distribution of chlamydia pneumonia infection in the atherosclerotic carotic artery[J]. Stroke, 1998, 29: 773.

[3]Mehta JL , Saldeen TG, Rand K. Interaction role of infection,inflammation and traditional risk factors in atherosclerosis and coronary artery disease[J]. J Am Coll Cardiol, 1998, 31: 1217.

[4] Jerffery L , Anderson MD, Facc JF, et al. Evaluation of C-reactive protein, an inflammatory marker and infectious serology as risk factors for coronary disease and myocardial infaction[J]. J Am Coll Cardiol, 1998, 32: 35.

[5] Tataru MC, Heinrich J , Junker R, et al. C-reactive protein and the severity of atherosclerosis in myocardial infarction patients with stable anginapectoris[J]. Eur Heart J , 2000, 21: 1000.

[6] Oltrona L , Ardissino D,Merlini PA , et al. C-reactive protein elevation and early outcome in patients with unstable anginapectoris[J]. Am J Cardiol, 1997, 80: 1002.

备注/Memo

备注/Memo:
收稿日期：2000-10-11.
更新日期/Last Update: 2002-01-01