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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:

2003年第2期

页码:

131-133

栏目:

临床研究

出版日期:

2003-03-01

文章信息/Info

Title:

Changes in atrial effective refractory period caused by paroxysmal atrial ventricular nodal and atrioventricular reentrant tachycardia in humans

作者:

梁延春¹; 贾国良²; 张清²; 王海昌²; 张殿新²

1.沈阳军区总医院心脏内科,辽宁 沈阳 110015;2.第四军医大学西京医院心脏内科,陕西 西安 710032

Author(s):

LIANG Yan-chun¹; JIA Guo-liang²; ZHANG Qing²; WANG Hai-chang²; ZHANG Dian-xin²

1.Department of Cardiology,General Hospital,Shen yang Command,Shen yang,Liao ning 110015, China; 2.Department of Cardiology,Xijing Hospital, Fourth Military Medical University,Xi'an,Shaanxi710032,China

关键词:

有效不应期; 心动过速; 房室结折返; 房室折返

Keywords:

effective refractory period; tachycardia; atrial ventricular nodal reentrant; atrial ventricular reentrant

分类号:

R541.75

DOI:

-

文献标识码:

A

摘要:

目的:探讨阵发性房室结折返性心动过速(AVNRT)和房室折返性心动过速(AVRT)对人心房有效不应期 (ERP)的影响。方法:对86例住院进行电生理检查和(或)导管射频消融术中出现自发或诱发的AVNRT和AVRT 患者,分别于AVNRT和AVRT发生前及发生终止后在500,400和300ms等不同基础周长下测量心房ERP。结 果:阵发性AVNRT和AVRT持续时间分别为14±6min及14±7min。AVNRT和AVRT终止后即刻心房ERP 缩短,与各自心动过速前相比均P<0.01。该缩短改变可以在5min内恢复。结论:阵发性AVNRT和AVRT可以 使人心房ERP缩短,造成短暂心房电重构。

Abstract:

AIM:To investigate the changes in atrial effective refractory period (ERP) after paroxysmal atrial ventricular nodal reentrant tachycardia (AVNRT) and atrioventricular reentrant tachycardia (AVRT) in humans.METHODS:In 86 patients admitted for electrophysiologyical testing and /or radio frequency catheter ablation,the ERPs were measured before and after paroxysmal AVNRT and AVRT at drive cycle lengths of 500,400 and 300ms.RESULTS:The durations of AVNRT and AVRT were 14±6 and 14±7 min respectively. Immediately upon AVNRT and AVRT conversion to sinus rhythm, atrial ERPs at each drive cycle lengths were significantly shortened (allP<0.01versus pre-tachycardia respectively).The post-tachycardia ERPs returned to the pre-tachycardia ERPs value after about 5min.CONCLUSION:In humans,paroxysmal AV NRT or AVRT of several minutes is sufficient to shorten the ERP and can cause atrial electrical remodeling

参考文献/References

[1]Wijffels MCEF,Kirchhof CJHJ,Dorland R,et al.Atrial fibrillation begets atrial fibrillation: a study in awake chronically instrumented goats[J].Circulation,1995,92:1954.

[2]Morillo CA,Klein GJ,Jones DL,et al.Chronic rapid atrial pacing: structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation [J].Circulation, 1995,91:1558.

[3]Zipes DP.Atrial fibrillation:A tachycardia-induced atrial cardiomyopathy [J]. Circulation, 1997,95:562.

[4]Chen YJ,Chen SA, Tai CT,et al.Role of electrophysiology and autonomic nervous system in patients with supraventricular tachycardia and paroxysmal atrial fibrillation[J].J Am CollCardio,1998,32:732.

[5]Franz MR,Karasik PL,LiC,et al.Electrical remodeling of the human atrium:similar effects in patients with chronic atrial fibrillation and atrial flutter [J]. J Am CollCardiol, 1997,30:1785.

[6]梁延春,贾国良,张清,等.人类自发的阵发性心房纤颤导致的心房有效不应期及其频率适应性的变化[J].中国心脏起搏与心电生理杂志, 2000, 14(2):96.

[7]Wang J,Liu L,Feng J,et al.Regional and functional factors determining induction and maintenance of atrial fibrillation in dogs[J].Am J Physiol,1996,271:H148.

[8] Wijffels MC, Kirchhof CJ, Dorland R, etal. Electrical remodeling due to atrial fibrillation in chronically instrumented conscious goats: role of neurohumoral changes, ischemia, atrial stretch,and high rate of electrical activation[J]. Circulation,1997,96:3710

备注/Memo

备注/Memo:

收稿日期：2002-1-24.

常用功能

更新日期/Last Update: 2003-03-01