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消融犬右肺静脉脂肪垫对心房及右上肺静脉电生理特性及房颤诱发的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第1期
页码:
28-30
栏目:
基础研究
出版日期:
2006-01-01

文章信息/Info

Title:
Effects of radiofrequency ablation of fat pad at right pulmonary veinatria junction on electrophysiology and atrial fibrillation induction of canine atria and the right superior pulmonary vein
作者:
杨玉辉 郑强荪 董建军 王洪涛 刘雄涛 卢延生 洪昌明
第四军医大学唐都医院心内科, 陕西 西安 710038
Author(s):
YANG Yu-hui ZHENG Qiang-sun DONG Jian-jun WANG Hong-tao LIU Xiong-tao LU Yan-sheng HONG Chang-ming
Department of Cardiology, Tangdu Hospital, Fourth Military Medical University, Xi′an,Shaanxi 710038, China
关键词:
心脏脂肪垫迷走神经有效不应期心房颤动射频消融
Keywords:
epicardial fat padvaguseffective refractory periodatrial fibrillationradiofrequency ablation
分类号:
R331.38;R541.75
DOI:
-
文献标识码:
A
摘要:
目的 探讨消融右肺静脉脂肪垫对心房及右上肺静脉电生理特性及房颤诱发的影响。方法 犬18只分别在颈部迷走神经未刺激和刺激的情况下,观察射频消融肺静脉脂肪垫前后心房不同部位及右上肺静脉有效不应期、房颤诱发率及房颤诱发窗口的变化。结果 在刺激迷走神经的情况下,与消融前相比,消融后高位右心房有效不应期延长(P<0.05),其余部位有效不应期无显著差异,消融后高位右心房房颤诱发率降低(P<0.01),房颤诱发窗口变窄(P<0.05),左心房(P<0.01)及右上肺静脉(P<0.01)房颤诱发率升高,诱发窗口增宽。同时,心房有效不应期离散度增加(P<0.01)。结论 消融右肺静脉脂肪垫使高位右心房房颤诱发率降低及房颤诱发窗口变窄,却使左房、右上肺静脉房颤诱发率升高及房颤诱发窗口增宽。
Abstract:
AIM To investigate the effects of radiofrequency ablation (RFA) of the fat pad at the right pulmonary veinatria junction (RPV fat pad) on electrophysiology and atrial fibrillation (AF) induction of atria and the right superior pulmonary vein (RSPV). METHODS Effective refractory period (ERP), incidence and induction window of AF of the atria and the RSPV with or without cervical vagal stimulation were examined before and after ablation of the fat pad. RESULTS RPV fat pad RFA increased only the ERP of the high right atrium (HRA) with vagal stimulation (P<0.05). RPV fat pad RFA decreased the incidence (P<0.01) and induction window(P<0.05) of AF at the HRA during vagal stimulation, while increased the incidence and induction window at the left atria (P<0.01) and the RSPV (P<0.01). RPV fat pad RFA increased the dispersion of the atrial ERP (P<0.01). CONCLUSION RPV fat pad RFA decreases the induction of AF at the HRA, while increases the induction at the left atria and the RSPV.

参考文献/References

[1]侯月梅,马丽. 起源于肺静脉的阵发性心房颤动的研究现状[J].中国心脏起搏与心电生理杂志,2004,18(3):161-164.

[2]Chiou CW, Zipes DP. Selective vagal denervation of the atria eliminates heart rate variability and baroreflex sensitivity while preserving ventricular innervation [J]. Circulation,1998,98(4):360-368.

[3]侯月梅,伊惠霞,Benjaming J,et al. 心脏脂肪垫在肺静脉灶性放电引发心房颤动中的作用 [J].中国心脏起搏与心电生理杂志,2003,17(5):377-380.

[4]Fareh S, Villemaire C, Nattel S. Importance of refractoriness heterogeneity in the enhanced vulnerability to atrial fibrillation induction caused by tachycardiainduced atrial electrical remodeling[J]. Circulation, 1998,98(20):2202-2209.

[5]周微微,任卫东.房颤发生机制研究进展[J].心脏杂志,2003,15(6):558-559.

[6]Haissaguerre M, Jais P, Shah DC, et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins[J]. N Engl J Med,1998,339(10):659-666.

[7]杜新平,卢才义,张建,等. 增龄对健康犬心房肺静脉电生理特性的影响[J].心脏杂志,2004,16(6):542-544.

备注/Memo

备注/Memo:
收稿日期:2005-07-13.基金项目:全军医学科研“十五”计划项目资助(No.01MB126)通讯作者:郑强荪,主任医师,博导,主要从事心律失常的临床和基础研究 Tel:(029)84777422 Email:qingshu@fmmu.edu.cn 作者简介:杨玉辉,硕士生Tel:(029)84777123 Email:yangyuhui008@126.com
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